Publications by authors named "Suleiman Mohammed Musa"
Ameliorative potentials of diosmin and hesperidin fractions on chlorpyriphos-induced changes in reproductive hormones, sperm characteristics, and testicular glycogen in male Wistar rats.
Naunyn Schmiedebergs Arch Pharmacol
November 2024
Article Synopsis
- Pesticide exposure, specifically from Chlorpyriphos, causes significant reproductive issues in male rats by damaging their sex organs and reducing hormone levels, sperm quality, and testicular glycogen.
- The study examined the effect of flavonoids (diosmin and hesperidin) on recovering reproductive functions in male Wistar rats after they were exposed to Chlorpyriphos for 60 days.
- Results showed that the rats treated with flavonoids had notably better levels of reproductive hormones, improved sperm parameters, and higher testicular glycogen compared to those treated only with Chlorpyriphos, indicating the potential protective effects of these antioxidant compounds against pesticide toxicity.
This study was to assess the anthelminthic potential of leaf extract against in experimentally infected broiler chickens. The extract and fractions were evaluated for in vitro inhibition and in vivo anthelmintic effects. Acute toxicity studies of extract revealed no sign of toxicity or death in birds at oral dose range of 1000-5000 and was considered safe.
View Article and Find Full Text PDFThe aim of this study was to investigate the ameliorative effect of Linn used traditionally against trypanosomosis. Twenty-five adult Wistar rats of both sex were individually infected intraperitoneally (IP) with 10 per ml of blood. Following establishment of infection, the rats were randomly divided into five groups of 5 rats each.
View Article and Find Full Text PDFEffects of melatonin on changes in cognitive performances and brain malondialdehyde concentration induced by sub-chronic co-administration of chlorpyrifos and cypermethrin in male Wister rats.
Asian Pac J Trop Biomed
April 2014
Objective: To evaluate the ameliorative effect of melatonin on sub-chronic chlorpyrifos (CPF) and cypermethrin (CYP)-evoked cognitive changes in male Wistar rats.
Methods: Fifty adult male Wistar rats, divided into five groups of ten rats each, were used for the study. Groups 1 and II were given distilled water and soya oil (2 mL/kg) respectively.