Publications by authors named "Suleiman Ibrahim Shelash Mohammad"
Article Synopsis
- Chemotherapy has significantly increased the survival rates of cancer patients, but it may also cause harmful effects on the heart, leading to potential heart failure.
- The main cause of chemotherapy-induced cardiotoxicity (CIC) is believed to be the production of free radicals, which creates oxidative stress.
- The review highlights the Sirtuin-1 (Sirt1)/Nuclear factor E2-associated factor 2 (Nrf2) signaling pathway as a promising method to combat CIC by reducing oxidative stress, inflammation, and cell death.
