The accuracy and clinical impact of intraoperative frozen section in determining the extent of surgical intervention in patients with early stage endometrial cancer.

The aim of this study was to compare intraoperative frozen section (FS) with the final pathology (FP), and determine its clinical impact in clinically apparent early stage endometrial cancer (EC) at the American University of Beirut Medical Center (AUBMC). Data for patients 18 years or older, with clinically apparent early stage, grade 1 or 2, endometrioid EC, who underwent hysterectomy ± lymph node dissection (LND) at AUBMC between January 1 1996 and June 30 2016 were retrospectively reviewed. 70 patients were included.

Fertility preservation in patients with mutation.

Evidence suggests a likely negative impact of deleterious mutations on female fertility. Hence, different studies have aimed to address the reproductive potential and performance of fertility preservation strategies in -mutated breast cancer patients with a prime focus on their safety and efficacy. However, several uncertainties exist in many domains of this field.