Publications by authors named "Sule Y Bilge"
Behçet's disease is a complex inflammatory vasculitis with a broad spectrum of clinical manifestations. The purpose of this study was to investigate the genetics underlying specific clinical features of Behçet's disease. A total of 436 patients with Behçet's disease from Turkey were studied.
View Article and Find Full Text PDFWe wanted to see how close we could get to our goal of treating rheumatoid arthritis (RA) without the use of glucocorticoids (GCs) in the disease-modifying antirheumatic drugs (DMARDs) era using real-life data. Established in 2017, the TReasure database is a web-based, prospective, observational cohort for Turkey. As of May 2019, there were 2,690 RA patients recorded as receiving biologic and targeted synthetic DMARDs (bDMARDs and tsDMARDs) therapy.
View Article and Find Full Text PDFThe aim of the present study was to examine the effects of age on mucocutaneous activity by using moderation analysis in Behçet's syndrome (BS). In this cross-sectional study, 887 BS patients (female : male, 481:406; mean age, 38.4 ± 10.
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- - The study aimed to assess patients' needs and measure oral ulcer activity in Behçet's syndrome (BS) using the Composite Index (CI) across 12 centers with 834 participants.
- - Results showed that 65.1% of patients had oral ulcers, with activity being higher in those receiving non-immunosuppressive treatments for mild disease, while immunosuppressive treatments were more effective in severe cases.
- - The findings indicated that oral ulcer activity is influenced by treatment type, disease severity, and duration, suggesting that the CI could be useful for evaluating treatment effectiveness in managing oral ulcers in BS.
Objective: Corticosteroids may cause hyperglycemia and diabetes mellitus (DM). Development of DM during long-term steroid use has been well studied; however, data regarding the short-term effects of steroid therapy are scarce. In this study, we aimed to detect the actual time of short-term steroid-induced hyperglycemia in patients without previous impaired glucose metabolism, and the ideal time (which day and in relation to meals) of glucose measurement.
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- The study looked at Familial Mediterranean fever (FMF), which is a disease where the body has improper inflammation, and focused on mutations in a specific part of the gene called exons.
- Researchers checked data from over 2,200 FMF patients to see how different mutations affected their health.
- They found that patients with mutations in exon 10 had worse symptoms than those with mutations in exon 2, meaning exon 10 mutations are associated with more severe cases of FMF.
Objective: The aim of this study was to evaluate whether there are clinical subgroups that may have different prognoses among FMF patients.
Methods: The cumulative clinical features of a large group of FMF patients [1168 patients, 593 (50.8%) male, mean age 35.
Vascular involvement is one of the major causes of mortality and morbidity in Behçet disease (BD). There are no controlled studies for the management of vascular BD (VBD), and according to the EULAR recommendations, only immunosuppressive (IS) agents are recommended. In this study, we aimed to investigate the therapeutic approaches chosen by Turkish physicians during the initial event and relapses of VBD and the association of different treatment options with the relapses retrospectively.
View Article and Find Full Text PDFObjectives: Paraneoplastic arthritis (PA) may mimic rheumatic diseases. While presenting the demographic and laboratory features of the patients diagnosed with PA, this study also aims to provide possible appropriate tools to differentiate the PA cases from early rheumatoid arthritis (ERA).
Methods: Sixty-five patients with PA (male/female: 43/22) from 15 different rheumatology clinics and 50 consecutive patients with ERA (male/female: 13/37) fulfilling the 2010 American College of Rheumatology (ACR) criteria for the diagnosis if the RA from Gaziantep Rheumatology Early Arthritis Trial (GREAT) as controls who were diagnosed at least 12 months before, were enrolled into study.
Objective: The primary aim of this study was to investigate the prevalence of amyloidosis and its related factors in a large number of FMF patients.
Methods: Fifteen centres from the different geographical regions of Turkey were included in the study. Detailed demographic and medical data based on a structured questionnaire and medical records were collected.
Objective: Patient-reported outcomes (PROs) are increasingly accepted to be among the major tools for outcome assessment in rheumatic disorders. In this study we aimed to assess quality of life (QoL), disability, anxiety and depression in patients with Takayasu's arteritis (TAK).
Methods: Patients followed with the diagnosis of TAK (n = 165) and healthy controls (HCs) (n = 109) were enrolled to the study.
Hypoparathyroidism and hyperparathyroidism may lead to spondylarthropathy or spondylarthropathy-like problems and crystal arthropathy, respectively. In this report, we present 2 cases with hypoparathyroidism and 1 case with hyperparathyroidism who developed spondylarthropathy-like disease, rheumatoid arthritis-like disease, and chondrocalcinosis, respectively. We briefly discussed relationship between calcium metabolism disorders and rheumatologic manifestations.
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