Enhanced Bioactivity of Chitosan-Alginate-Riboflavin Liquid-Exfoliated Molybdenum Disulfide Nanosheets for Bone Tissue Engineering Applications.

Bone tissue engineering is a growing field that provides solutions for the treatment of bone deformities, injuries, diseases, and anomalies by replacing autograft and allograft procedures. Various scaffolding materials have been used for the construction of bone tissue, including metals, ceramics, and polymers. This study investigates an innovative liquid exfoliation approach for the production of molybdenum disulfide (MoS) nanosheets using riboflavin (RF-MoS) as an exfoliation agent and subsequently analytically characterized for the development of bone scaffolding system.

Photodynamic therapy for oral mucositis in cancer patients- a systematic review and meta-analysis.

Aim: This systematic review aimed to evaluate the efficacy of photodynamic therapy (PDT) in reducing the severity of chemotherapy-induced oral mucositis, and associated symptoms in cancer patients compared to standard care or other interventions.

Materials And Methods: A comprehensive literature search identified seven relevant studies (randomized controlled trials and non-randomized clinical trials) published between January 1, 2000, and May 31, 2024. The data analysis was carried out using the standardized mean difference as the outcome measure.

Fluoride Concentrations in Different Brands of Toothpaste Marketed in Saudi Arabia.

Objectives: This study aimed to evaluate the concentrations of total fluoride (TF), total soluble fluoride (TSF) and ionic fluoride (IF) in various toothpaste brands marketed in Saudi Arabia and compare them with the labelled values.

Methods: Twenty toothpaste brands were randomly selected from supermarkets and hypermarkets in Riyadh, Saudi Arabia. For each brand, two samples from different production batches were purchased and labelled as sample 1 and sample 2.

Photodynamic therapy: An emerging therapeutic modality in dentistry.

Photodynamic Therapy (PDT) is a rapidly evolving, non-invasive treatment modality with considerable promise in dental pharmacotherapeutics. This review article comprehensively examines PDT, beginning with its principles and then delving into its diverse applications in dentistry, including periodontal disease, endodontics, oral cancer, dental implants, and dental caries. Each area presents the latest research and discusses the potential benefits and challenges.

Oral health status and dental treatment needs in children with autism spectrum disorder.

Objective: To evaluate oral health care practices, health status, and dental treatment needs in children with Autism Spectrum Disorder (ASD).

Methods: This cross-sectional study included 96 children diagnosed with ASD per the DSM-V criteria and 96 typically developing healthy children. The WHO form assessed oral health status and dental treatment needs.

Efficacy of Xenogeneic Collagen Matrices in Augmenting Peri-Implant Soft Tissue: A Systematic Review and Meta-Analysis.

Background: Xenogenic collagen matrices (XCMs) are gaining popularity for soft tissue augmentation in dental implants; yet, gaps exist in our understanding of their comparative effectiveness.

Objective: This systematic review and meta-analysis focuses on studies that utilize soft tissue augmentation techniques for dental implants to improve keratinized mucosa width (KMW), soft tissue thickness (STT), and soft tissue volume (STV). We compared porcine collagen matrices with autogenous grafts when no bone grafts were utilized.

Differential Expression of Immunohistochemical Markers in Ameloblastoma & Ameloblastic Carcinoma: A Systematic Review and Meta-analysis of observational studies.

Background: Differentiating between ameloblastoma (AB) and ameloblastic carcinoma (AC) is difficult, especially when AB has atypical cytological characteristics or an uncommon clinical history. This systematic review and meta-analysis aimed to elucidate the differential expression of immunohistochemical markers between AB and AC.

Methods: We conducted a thorough search of PUBMED and SCOPUS according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines to identify cross-sectional studies that compared the expression of immunohistochemical markers in AB and AC.

Fish scale-derived hydroxyapatite for alveolar ridge preservation.

Alveolar ridge resorption following tooth extraction poses significant challenges for future dental restorations. This study investigated the efficacy of fish scale-derived hydroxyapatite (FSHA) as a socket preservation graft material to maintain alveolar bone volume and architecture. FSHA was extracted from *Labeo rohita* fish scales and characterized using Fourier transform infrared (FTIR) analysis.

Association between metabolic syndrome and salivary MMP-8, myeloperoxidase in periodontitis.

Objective: This study investigated the effect of metabolic syndrome (MetS) on periodontal clinical parameters and salivary biomarkers' matrix metalloproteinase-8 (MMP-8) and myeloperoxidase (MPO) in patients with periodontitis.

Methods: A total of 120 participants aged 25-55 were categorized into three groups: MetS with periodontitis (n = 40); systemically healthy with periodontitis (n = 40); and systemically and periodontally healthy controls (n = 40). Data collected included systemic parameters like waist circumference (WC), blood pressure (BP), high- and low-density lipoproteins, triglycerides (TG), fasting blood sugar (FBS), and glycated hemoglobin (HbA1c).

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth.

In the realm of regenerative medicine and therapeutic applications, stem cell research is rapidly gaining traction. Dental pulp stem cells (DPSCs), which are present in both deciduous and permanent teeth, have emerged as a vital stem cell source due to their accessibility, adaptability, and innate differentiation capabilities. DPSCs offer a readily available and abundant reservoir of mesenchymal stem cells, showcasing impressive versatility and potential, particularly for regenerative purposes.

Fabrication and characterizations of simvastatin-containing mesoporous bioactive glass and molybdenum disulfide scaffold for bone tissue engineering.

Due to the limitations of the current treatment approaches of allograft and autograft techniques, treating bone disorders is a significant challenge. To address these shortcomings, a novel biomaterial composite is required. This study presents the preparation and fabrication of a novel biomaterial composite scaffold that combines poly (D, L-lactide-co-glycolide) (PLGA), mesoporous bioactive glass (MBG), molybdenum disulfide (MoS), and simvastatin (Sim) to address the limitations of current bone grafting techniques of autograft and allograft.

Knowledge of the monkeypox 2022 outbreak among dental hygienists and students in Saudi Arabia: A cross-sectional study.

Objective: This study aimed to assess the knowledge of monkeypox infection among dental hygiene professionals and students in Saudi Arabia.

Methods: A cross-sectional study was conducted among a convenience sample of dental hygiene professionals (n = 259). The questionnaire was developed based on previous literature, and descriptive analysis and a Chi-square test were performed.

Transforming Dental Caries Diagnosis Through Artificial Intelligence-Based Techniques.

Diagnosing dental caries plays a pivotal role in preventing and treating tooth decay. However, traditional methods of diagnosing caries often fall short in accuracy and efficiency. Despite the endorsement of radiography as a diagnostic tool, the identification of dental caries through radiographic images can be influenced by individual interpretation.

Osseointegration of Tantalum Trabecular Metal in Titanium Dental Implants: Histological and Micro-CT Study.

This study aimed to investigate the impact of the Tantalum Trabecular Metal dental implant design on implant stability and the process of osseointegration following its placement in the rabbit femoral condyle. The subjects for the experiment consisted of 10 New Zealand white rabbits. Twenty implants, comprising 10 Trabecular Metal (TM) and 10 Traditional Screw Vent (TSV) implants, were placed into the femoral condyles of these rabbits.

Oral lesions in human monkeypox disease and their management.

Objective: The current outbreak of human monekypox (MPX) in several endemic and non-endemic regions in 2022 has generated significant international attention. Despite the early classification as zoonotic, MPXV has demonstrated the potential for human-to-human transmission through close contact with lesions, body fluids, respiratory droplets, and contaminated materials. Therefore, our objective was to elaborate on the oral lesions in human MPX and their management.

Perceptions of Indian Healthcare Practitioners Regarding the 2022 Outbreak of Monkeypox Disease.

Introduction Although only a few cases of monkeypox have been reported in India so far, it is vital for healthcare practitioners to have sufficient knowledge about its epidemiology, clinical presentation, diagnosis, and management. Therefore, this study aimed to understand the perception of Indian healthcare practitioners regarding the 2022 outbreak of monkeypox disease. Methods A cross-sectional survey was conducted among 500 medical and dental practitioners from various regions of Kerala, India.

Remineralizing Potential of Natural Nano-Hydroxyapatite Obtained from in Artificially Induced Early Enamel Lesion: An In Vitro Study.

Dental caries is a common problem in adolescents, leading to permanent loss of teeth or cavitation. Caries is a continuous process wherein demineralization and remineralization occur regularly. Hydroxyapatite (HA) is one of the most biocompatible and bioactive materials, as it closely resembles the mineral composition of teeth.