Complete genome sequence of type A strain (X58540) isolated from cattle feces.

The full genome sequence of type A strain X58540 found in fecal samples from cattle exhibiting clinical symptoms of chronic botulism is presented here. The genome of X58540 consists of 2,371,631 bp with a GC content of 28.17% and is predicted to include 2,157 coding sequences.

The roles of striatal serotonin and L -amino-acid decarboxylase on L-DOPA-induced Dyskinesia in a Hemiparkinsonian rat model.

The administration of L: -DOPA is the standard treatment for Parkinson's disease (PD). However, the symptomatic relief provided by long-term administration may be compromised by L: -DOPA-induced dyskinesia (LID) that presents as adverse fluctuations in motor responsiveness and progressive loss of motor control. In the later stages of PD, raphestriatal serotonin neurons compensate for the loss of nigrostriatal dopamine (DA) neurons by converting and releasing DA derived from exogenous L: -DOPA.