Comorbidity of dementia and age-related macular degeneration calls for clinical awareness: a meta-analysis.

Aim: To determine the association between dementia and age-related macular degeneration (AMD) using meta-analysis.

Methods: We searched in the MEDLINE, EMBASE, Web of Knowledge, PsycInfo and Cochrane database of systematic reviews for studies published from March 1959 to March 2018. We included cross-sectional, case-control and cohort studies that evaluated the association of dementia/Alzheimer's disease (AD) with AMD (as outcome) and the association of AMD with dementia/AD (as outcome).