Epinephrine treatment is infrequent and biphasic reactions are rare in food-induced reactions during oral food challenges in children.

Background: Data about epinephrine use and biphasic reactions in childhood food-induced anaphylaxis during oral food challenges are scarce.

Objective: To determine the prevalence and risk factors of reactions requiring epinephrine and the rate of biphasic reactions during oral food challenges (OFCs) in children.

Methods: Reaction details of positive OFCs in children between 1999 and 2007 were collected by using a computerized database.