Publications by authors named "Sujit Saha"
Heat stress is one of the primary environmental factors that harm both the productivity and health of buffaloes. The current study was conducted to estimate the threshold of temperature humidity index (THI) and genetic features for milk yield of first-lactation Mehsana buffaloes using an univariate repeatability test-day model. The data included 130,475 first lactation test-day milk yield (FLTDMY) records of 13,887 Mehsana buffaloes and the daily temperature and humidity.
View Article and Find Full Text PDFIntroduction: Anti-glomerular basement membrane (GBM) disease is a rare cause of glomerulonephritis usually mediated by IgG antibodies and is associated with ANCA-associated glomerulonephritis in up to 50% of cases. IgA-mediated anti-GBM disease is extremely rare and presents diagnostic difficulties as circulating IgA antibodies will not be detected by standard serological tests for anti-GBM disease.
Case Presentation: We present the case of a 67-year-old man with rapidly progressive glomerulonephritis requiring haemodialysis at presentation.
Fertility is an important trait associated with reproductive performance and animal welfare concern. Lethal alleles affect fertility through early embryonic death, abortions, and stillbirth depending on the genetic expression of the allele. Holstein Friesian and Jersey are two major Bos taurus breeds used widely for increasing milk yield along with purebreds of Bos indicus breeds like Gir, Kankrej, Sahiwal, and Tharparkar.
View Article and Find Full Text PDFFibrosis is the pathophysiological hallmark of progressive chronic kidney disease (CKD). The kidney is a highly metabolically active organ, and it has been suggested that disruption in its metabolism leads to renal fibrosis. We developed a longitudinal mouse model of acute kidney injury leading to CKD and an model of epithelial to mesenchymal transition to study changes in metabolism, inflammation, and fibrosis.
View Article and Find Full Text PDFArticle Synopsis
- The COVID-19 pandemic saw increased rates of acute kidney injury (AKI) in critically ill patients, raising the need for renal replacement therapy (RRT), particularly challenging due to the high demand in ICUs.
- The study evaluated the safety and efficacy of peritoneal dialysis (PD) as an alternative to continuous renal replacement therapy (CRRT) by analyzing catheter insertion and patient outcomes.
- Results showed successful catheter insertions with no reported complications, stable patient conditions post-insertion, and a median 94.6% RRT coverage through PD, indicating it as a viable option for managing AKI in ventilated COVID-19 patients.
Cytomegalovirus (CMV) infection is the most common viral infection in liver transplant recipients, affecting post-transplant patients and graft survival. Recent advances in diagnosis and management of CMV have led to marked reduction in incidence, severity, and its associated morbidity and mortality. CMV DNA assay is the most commonly used laboratory parameter to diagnose and monitor CMV infection.
View Article and Find Full Text PDFBackground: Intra-abdominal hypertension (IAH) and abdominal compartment syndrome commonly occur in patients with liver disease.
Aims: We compared haemodynamic variables pre- and post-abdominal decompression in patients with acute Budd-Chiari syndrome (BCS) and patients with chronic liver disease (CLD), ascites and IAH.
Methods: Patients with IAH admitted to the Liver ICU, King's College Hospital were studied.