Publications by authors named "Sujir Pritha Nayak"
Resuscitation of an infant with surgical complications includes both perioperative and post-operative management. In most cases this requires a multidisciplinary approach to achieve the best outcomes. Challenges include immediate expert management at infant delivery with the use of protocolized care, available anesthesia expertise, close monitoring of electrolytes with prompt attention to fluid status, and meticulous pain management.
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- The study aimed to evaluate short-term outcomes such as mortality and length of stay for extremely low birth weight infants with spontaneous intestinal perforation, comparing three surgical approaches: peritoneal drain (PD), laparotomy after PD (PD-LAP), and straight laparotomy (LAP).
- Out of 729 identified infants, those treated with PD had lower gestational ages and higher infection rates, with PD associated with higher mortality rates compared to PD-LAP and LAP in initial analysis, but this link was not confirmed in more complex statistical models.
- Ultimately, the findings suggest that the type of initial surgical approach does not significantly affect mortality or length of stay for these infants, indicating that other factors such
Objective: Neonates born with fetal inflammatory response (FIR) are at increased risk for adverse neonatal outcomes. Our objective was to determine whether FIR and its severity is associated with severity of necrotizing enterocolitis (NEC) in preterm infants.
Methods: A case-control retrospective study of infants <33 weeks gestational age or <1500 g birthweight, including 260 with stage I-III NEC and 520 controls matched for gestational age.
Objective: To evaluate the relationship between cholestasis and outcomes in medical and surgical necrotizing enterocolitis (NEC).
Study Design: A retrospective analysis of prospectively collected data from 1472 infants with NEC [455 medical (mNEC) and 1017 surgical (sNEC)] from the Children's Hospital Neonatal Database.
Results: The prevalence of cholestasis was lower in mNEC versus sNEC (38.
Objective: Early onset infection (EOI) in gastroschisis is rare. Excess antibiotic exposure in neonates increases necrotizing enterocolitis and mortality. We evaluated antibiotic exposure and EOI in gastroschisis.
View Article and Find Full Text PDFObjectives: To evaluate variability in antibiotic duration for necrotizing enterocolitis (NEC) and associated clinical outcomes.
Study Design: Five-hundred ninety-one infants with NEC (315 medical; 276 surgical) were included from 22 centers participating in Children's Hospitals Neonatal Consortium (CHNC). Multivariable analyses were used to determine predictors of variability in time to full feeds (TFF) and length of stay (LOS).
Background: Lipid-injectable emulsions (ILEs) are a necessity for neonates dependent on parenteral nutrition (PN). In this manuscript, we describe the patterns of ILE use in neonatal intensive care units (NICUs) in the United States (US).
Methods: An electronic survey was sent to 488 NICUs across the US between December 2020 and March 2021.
Objectives: To examine characteristics and outcomes of T18 and T13 infants receiving intensive surgical and medical treatment compared to those receiving non-intensive treatment in NICUs.
Study Design: Retrospective cohort of infants in the Children's Hospitals National Consortium (CHNC) from 2010 to 2016 categorized into three groups by treatment received: surgical, intensive medical, or non-intensive.
Results: Among 467 infants admitted, 62% received intensive medical treatment; 27% received surgical treatment.
Does the initial surgery for necrotizing enterocolitis matter? Comparative outcomes for laparotomy vs. peritoneal drain as initial surgery for necrotizing enterocolitis in infants <1000 g birth weight.
J Pediatr Surg
April 2019
Purpose: Quantify short-term outcomes associated with initial surgery [laparotomy (LAP) vs. peritoneal drain (PD)] for necrotizing enterocolitis (NEC) in extremely-low-birth-weight (ELBW) infants.
Methods: Using the Children's Hospitals Neonatal Database, we identified ELBW infants <32 weeks' gestation with surgical NEC (sNEC).