Publications by authors named "Sujata Thakurta"
Background: Lung cancer screening (LCS) using low-dose CT imaging is recommended for people at high risk of dying of lung cancer. Communication strategies for clinicians have been recommended, but their influence on patient-centered outcomes is unclear.
Research Question: How do patients experience communication and decision-making with clinicians when offered LCS?
Study Design And Methods: We performed semistructured interviews with 51 patients from three institutions with established LCS programs.
Background: Systematic reviews (SRs) depend on comprehensive searches for evidence to provide balanced, accurate results. Requesting published and unpublished studies from pharmaceutical manufacturers has been proposed as a method to engage industry stakeholders and potentially reduce reporting bias. The Drug Effectiveness Review Project (DERP) has been requesting such evidence since 2003; the purpose of this study was to retrospectively evaluate the type and impact of the evidence received.
View Article and Find Full Text PDFPurpose: The current standard of care for surgically eligible stage I non-small cell lung cancer (NSCLC) is surgical resection, but emerging data suggest that stereotactic body radiation therapy (SBRT) is potentially as effective as surgery. However, specialist views of the current evidence about SBRT and how they would incorporate a randomized controlled trial (RCT) into practice is unclear. We sought to understand specialist opinions about evidence regarding treatment of stage I NSCLC and how this translates into practice and clinical trial implementation.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates smoking behaviors among Veterans, highlighting the need to identify unique military and sociodemographic factors that affect smoking rates to improve cessation efforts.
- Data from the 2010 National Survey of Veterans was analyzed, revealing that 17% of respondents were current smokers, with certain demographic and military experiences influencing smoking status.
- Findings indicate that factors like female gender, low educational attainment, and exposure to trauma during service can increase smoking likelihood, while indicators such as higher income and service-related disabilities correlate with being a non-smoker.
Objective: It is important to identify separate publications that report outcomes from the same underlying clinical trial, in order to avoid over-counting these as independent pieces of evidence.
Methods: We created positive and negative training sets (comprised of pairs of articles reporting on the same condition and intervention) that were, or were not, linked to the same clinicaltrials.gov trial registry number.
Objective: To evaluate the comparative benefits and harms in both mother and child of antidepressant treatment for depression in pregnant or postpartum women.
Data Sources: MEDLINE, the Cochrane Library, CINAHL, Scopus, ClinicalTrials.gov (inception to July 2013), manufacturers, and reference lists.
Antidepressant Treatment of Depression During Pregnancy and the Postpartum Period.
Evid Rep Technol Assess (Full Rep)
July 2014
Objectives: To evaluate the benefits and harms of pharmacological therapy for depression in women during pregnancy or the postpartum period.
Data Sources: Cochrane Database of Systematic Reviews, the Cochrane Central Register of Controlled Trials, the Cumulative Index to Nursing and Allied Health Literature (CINAHL), MEDLINE, Scopus, ClinicalTrials.gov, and Scientific Information Packets from pharmaceutical manufacturers.
Purpose: We conducted a study to examine the efficacy, effectiveness, and harms of pramlintide as adjunct therapy in adults and children with type 1 or type 2 diabetes.
Methods: We searched multiple bibliographic databases to January 2010, the US Food and Drug Administration Web site, and other sources to identify randomized controlled trials (RCTs) fulfilling inclusion criteria. Syntheses were qualitative because data were too heterogeneous for meta-analysis.