Publications by authors named "Sujata C Chakraborty"
Article Synopsis
- Fanconi anemia (FA) is a genetic disorder that causes bone marrow failure, physical anomalies, and an increased risk of cancer.
- The study aimed to determine if XRCC2 is an FA gene by correcting cellular defects associated with the disorder in patient-derived cells.
- The findings showed that wild-type XRCC2 rectified several FA-related issues, confirming XRCC2/FANCU as an FA gene, while also providing insights into its role in DNA repair processes.
Hum Mol Genet
September 2015
Article Synopsis
- Fanconi anemia (FA) is a rare disorder that causes problems like bone marrow failure and makes people more likely to get cancer.
- Scientists found a patient with two mutations in a gene called UBE2T, which is important for repairing DNA.
- They discovered that UBE2T is a real FA gene and could also be linked to a rare chance of getting breast cancer.
