Chronic Eosinophilic Leukemia Presenting Predominantly with Cutaneous Manifestations.

A 37-year-old male presented with severe oral and genital mucosal ulcers, lichenoid eruption and twenty-nail dystrophy. Systemic examination was normal, except for anemia. On investigations, he was found to have persistently elevated peripheral eosinophilia, absolute eosinophil count >5000/mm(3), bone marrow showing increased eosinophilic precursors, and infiltration by atypical cells.

Hansen's disease in association with immune reconstitution inflammatory syndrome.

Immune reconstitution inflammatory syndrome is characterized by a paradoxical worsening of an existing infection or disease process, soon after initiation of highly active antiretroviral therapy. The first case of leprosy presenting as immune reconstitution inflammatory syndrome was published in 2003. Here we report a case of Hansen's disease borderline tuberculoid presenting with type 1 lepra reaction 5 months after initiation of highly active antiretroviral therapy.

A study of the prevalence of smear-positive leprosy cases in a tertiary care center in the post-elimination phase of leprosy.

Background: India has declared leprosy to be eliminated in the country, according to the WHO criteria of attaining a prevalence of less than 1 in 10,000. However, smear-positive leprosy cases are frequently being encountered.

Methods: This is an 18-year retrospective study done in the Department of Dermatology and Venereology, Government Medical College, Trivandrum.