[Effect of Acupuncture on Expression of Glial Fibrillary Acidic Protein in Hippocampus and Prefrontal Cortex and Serum Interleukin-10 in Chronic Restraint Stress Depression Rats].

Objective: To observe the effect of acupuncture on the expression of glial fibrillary acidic protein (GFAP) in hippocampus and prefrontal cortex and the level of serum interleukin 10 (IL-10) in rats with depression, so as to explore its mechanism underlying improvement of depression.

Methods: Thirty-two male SD rats were randomly divided into four groups: control, model, acupuncture, and medication (Fluoxetine, Flu) (=8 rats in each). The depression model was established by using chronic restraint stress (constraint, fasting, water deprivation, etc.

[Effect of Warm-needle-moxibustion on Behavior Reactions and TNF-α and MMP-3 Contents in Knee Cartilage of Rabbits with Knee Osteoarthritis].

Objective: To observe the effect of warm-needle-moxibustion on behavior changes and the levels of tumor necrosis factor-α (TNF-α) and matrix metalloproteinase-3 (MMP-3) in the knee cartilage tissue of rabbits with knee osteoarthritis (KOA) so as to explore its mechanisms in relieving KOA.

Methods: Thirty male Japanese white rabbits were randomly divided into normal, model and treatment groups (=10 in each group). The KOA model was established by using immobilization me-thod.

[Effect of Warm-needle Moxibustion on Expression of Transfer Growth Factor-β1 and Insulin- like Growth Factor I in Knee Cartilage of Rabbits with Knee Osteoarthritis].

Objective: To observe the effect of warm-needle moxibustion on transfer growth factor-β1 (TGF-β1) and insulin-like growth factor I (IGF-I) expression in knee cartilage of knee osteoarthritis (KOA) rabbits so as to explore its underlying mechanism in improving osteoarthritis.

Methods: Thirty Japanese white rabbits were randomly and equally divided into control, model and warm-needle moxibustion(treatment) groups (n = 10 in each group). The KOA model was made by immobilization of the rabbit knee.