Publications by authors named "Sui Poh Tee"
Objectives: Melioidosis, caused by Burkholderia pseudomallei, is prevalent in rural areas of Malaysia. The aim of this study is to delineate the epidemiology and predictors of mortality from melioidosis in Kapit district, Sarawak.
Methods: For this retrospective study of patients with culture-confirmed melioidosis admitted to Kapit Hospital, Sarawak, Malaysia, between July 2016 and July 2019, epidemiological, clinical and microbiological data were obtained.
Article Synopsis
- Different individuals (humans and animals) exhibit varied learning speeds for the same tasks, with traditional models attributing this variability mainly to differences in the learning rate of synaptic updates.
- Research indicates that the initial connectivity between neurons is a significant factor influencing learning speed, especially when connections are updated in a multiplicative way.
- Experiments with mice showed that while all subjects learned an auditory discrimination task, those with pre-trained connections learned faster during a subsequent task reversal, highlighting the value of multiplicative learning rules and initial synaptic weights in understanding biological learning dynamics.
We explored for relationships between SCN5A haploinsufficiency, implicated in clinical arrhythmogenicity, and right ventricular (RV) conduction disorders in Langendorff-perfused, male and female, and young (3 months) and old (>12 month old) Scn5a ( +/-) and wild type (WT) hearts. The investigated conditions of genotype, age, and sex affected latencies but not repolarization time courses of RV monophasic action potentials. This prompted examination of the patterns of RV epicardial activation, its dispersion, and their interrelationships as possible arrhythmic mechanisms using a 64-channel, multi-electrode array.
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