Publications by authors named "Suheyla Uzun"
Investigation of circadian rhythm gene Per3 in diabetic neuropathy.
Nucleosides Nucleotides Nucleic Acids
June 2024
Article Synopsis
- Diabetic neuropathy (DN) is a complication of diabetes that may be influenced by disturbances in circadian rhythms and rhythm genes.
- This study examined the relationship between the VNTR polymorphism of the PER3 gene and diabetic neuropathy in a sample that included diabetes patients, DN patients, and a control group.
- The findings indicated no significant link between PER3 polymorphism and diabetic neuropathy; however, there was a notable association between the PER3 gene and diabetes itself.
Introduction: Raynaud's phenomenon (RP) is a multifactorial disorder. If any underlying disease cannot be determined to be responsible for RP, then it is considered to be the primary RP (pRP). We aimed to investigate the differences between laboratory markers and impaired endothelial function in pRP.
View Article and Find Full Text PDFPurpose: The aim of this study was to evaluate whether the VNTR intron 4b/4a variant in the eNOS gene is associated with type 2 diabetes mellitus (T2DM) and DPN.
Methods: A total of 598 subjects were enrolled in the study. eNOS VNTR 4b/4a variant was genotyped by polymerase chain reaction (PCR) method.
Prevalence of Nonalcoholic Fatty Liver Disease in Familial Mediterranean Fever.
Endocr Metab Immune Disord Drug Targets
June 2021
Introduction: Nonalcoholic fatty liver disease (NAFLD) is closely associated with metabolic syndrome (MetS), insulin resistance (IR) and chronic inflammation. Although familial Mediterranean fever (FMF) patients have no symptoms in the periods between attacks, their subclinical inflammation continues. The aim of the present study was to determine the NAFLD frequency in FMF patients and to evaluate their MetS, IR and lipid profiles.
View Article and Find Full Text PDFIL-1β and IL-1Ra Variant Profiles in Turkish Patients with Diabetic Peripheral Neuropathy.
Endocr Metab Immune Disord Drug Targets
June 2019
Background: Diabetic peripheral neuropathy (DPN) is one of the most common complications of Type 2 diabetes mellitus (T2DM). This study was conducted to investigate the possible association between interleukin-1β (IL-1β) rs16944 /IL-1 receptor antagonist (IL-1Ra) VNTR variants and genetic susceptibility to DPN in a Turkish cohort.
Methods: A total of 200 subjects were enrolled in this study, 98 patients with DPN and 102 cases of age and sex-matched healthy controls.