Background And Objectives: Gemcitabine is an active agent in pancreatic cancer, with known radiosensitizing properties. Therefore, a phase II study was conducted to evaluate the efficacy of gemcitabine combined with radiation therapy in patients with localized unresectable adenocarcinoma of the pancreas.
Methods: Weekly gemcitabine at a dose of 1,000 mg/m(2) for 7 weeks was given as an induction phase.