Safety assessment of Cissus quadrangularis extract (CQR-300): subchronic toxicity and mutagenicity studies.

Cissus quadrangularis has been used for centuries for therapeutic and culinary purposes. Extract from this plant (CQR-300) has been claimed for its health benefits. The objective of present investigation was to delineate adverse effects, if any, of CQR-300 in subchronic toxicity, and gentotoxicity studies.