Publications by authors named "Suhaniya N S Samarasinghe"

Article Synopsis
  • Polycystic ovary syndrome (PCOS) is a leading cause of infertility due to a lack of ovulation, and obesity worsens these reproductive issues; bariatric surgery might improve fertility rates but hasn't been vigorously tested against other treatments.
  • This study involved 80 women with PCOS and obesity, who were randomly assigned to either undergo bariatric surgery (vertical sleeve gastrectomy) or receive behavioral and medical therapy to compare their impact on ovulation rates over a year.
  • The study aimed to track the number of confirmed ovulatory events through regular progesterone testing, with results pending since participants were recruited between February 2020 and February 2021, and some participants dropped out of the trial.
View Article and Find Full Text PDF

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive-age women. This systematic review, meta-analysis, and meta-regression aims to compare the effect of insulin sensitizer pharmacotherapy on metabolic and reproductive outcomes in women with PCOS and overweight or obesity. We searched online databases MEDLINE via OVID, EMBASE, Clinicaltrials.

View Article and Find Full Text PDF

Polycystic ovary syndrome (PCOS) is the most common endocrine condition in premenopausal women and is a common cause of anovulatory subfertility. Although obesity does not form part of the diagnostic criteria, it affects a significant proportion of women with PCOS and is strongly implicated in the pathophysiology of the disease. Both PCOS and obesity are known to impact fertility in women; obesity also reduces the success of assisted reproductive technology (ART).

View Article and Find Full Text PDF