Publications by authors named "Suhan Bae"

Article Synopsis
  • The study investigates the relationship between gut microbiota and regulatory T cells (Tregs) in chickens, focusing on how antibiotics affect Treg populations.
  • Researchers found that treating chickens with antibiotics significantly reduced certain Treg cell types in their cecal tonsils, linking these changes to Gram-positive bacteria like Clostridia.
  • Supplementing the antibiotic-treated chickens with acetate helped recover the Treg populations, highlighting the role of acetate and its receptor GPR43 in regulating T cell activity in the gut.
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Organic acids have long been known for their beneficial effects on growth performance in domestic animals. However, their impact on immune responses against viral antigens in chickens is unclear. The present study aimed to investigate immunological parameters in broilers immunized with a H9N2 vaccine and/or fed a diet containing organic acids (citric, formic, and lactic acids).

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Intestinal barrier is the first line of defense inside the body and comprises intercellular tight junction (TJ) proteins that regulate paracellular permeability. Deoxynivalenol (DON), a fungal metabolite often found in the contaminated food of domestic animals, is known to impair intestinal barrier function and may be involved in intestinal inflammation. Unlike in humans and mice, the importance of Toll-like receptor (TLR) 2 expressed in porcine intestinal epithelial cells is largely unclear.

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