Current Trends of Drug Resistance Patterns of Infection in Blood Transfusion-dependent Thalassemia Patients.

Objective: The present study aimed to evaluate the current trends of drug resistance patterns of infection in blood transfusion-dependent thalassemia patients.

Study Design: This study was a cross sectional study, conducted at the Liaquat University of Medical and Health Sciences, Jamshoro/Hyderabad, Sindh, Pakistan from October 2014 to January 2016.

Subjects And Methods: Of 921 blood samples, strains were isolated from 100 blood samples.

Berberine protects against metformin-associated lactic acidosis in induced diabetes mellitus.

Objectives: Causality of occurrence of metformin-associated lactic acidosis (MALA) is a clinical problem. Currently, there is no drug available to prevent MALA. The present study was conducted to evaluate the protective effect of Berberine (BBR) against MALA in induced diabetic rat model.

Serum enolase-2, high-sensitivity C-reactive protein, and serum cholesterol in smear-positive drug-naïve pulmonary tuberculosis.

Background: Pulmonary tuberculosis (PTB) is a chronic granulomatous disease caused by . The present study determined the serum human enolase-2 (ENO-2), high-sensitive C-reactive protein (hs-CRP), and serum cholesterol levels as biological marker of disease activity and treatment response in smear-positive drug-naïve PTB.

Materials And Methods: This case-control study was done in the Department of Medicine, Liaquat University of Medical and Health Sciences (LUMHS), Jamshoro/Hyderabad, Sindh, from January 2015 to April 2016.