Distribution of 22 Single Nucleotide Polymorphisms in 13 Cytokine Genes in Malays, Chinese, and Indians in Peninsular Malaysia.

Cytokines are cell signaling glycoproteins that are particularly important in immunity and inflammatory responses. Therefore, variations, such as single nucleotide polymorphisms (SNPs), in genes encoding for cytokines may have important consequences for their roles in health. A total of 222 unrelated, healthy, and un-admixed Malays ( = 97), Chinese ( = 77), and Indians ( = 48) with a median age of 30 years old (range 21-50) were typed for 22 cytokine gene SNPs: T/C, ( T/C, T/C), T/C, T/C, G/A, C/A, A/T, ( C/T, G/C), ( A/G, A/G) ( G/T, T/G), ( T/G, T/C, - T/C), ( C/G, G/A), and ( G/A, C/T, A/C).