Genomic insight into the salt tolerance and proteolytic activity of Bacillus subtilis.

We assessed the salt tolerance and proteolytic activity of 40 genome-published Bacillus subtilis strains isolated from fermented Korean foods to illuminate the genomic background behind the functionality of B. subtilis in high-salt fermentation. On the basis of the salt tolerance and phenotypic proteolytic activity of the 40 strains, we selected five strains exhibiting different phenotypic characteristics.

Antibiotic susceptibility of Bacillus velezensis.

We evaluated the antibiotic minimum inhibitory concentrations (MICs) of 123 Bacillus velezensis strains predominantly isolated from fermented soybean foods from Korea. When the 2018 European Food Safety Authority breakpoint values for Bacillus spp. were applied, all the strains were sensitive to chloramphenicol, clindamycin, erythromycin, gentamicin, kanamycin, tetracycline and vancomycin, and eight strains (6.

Safety and Technological Characterization of and Isolates from Fermented Soybean Foods of Korea.

We evaluated the antibiotic susceptibilities, hemolytic activities, and technological properties of 36 strains and 49 strains predominantly isolated from fermented soybean foods from Korea. Most of the strains were sensitive to chloramphenicol, erythromycin, gentamycin, kanamycin, lincomycin, oxacillin, tetracycline, and trimethoprim. However, 23 strains exhibited potential phenotypic acquired resistance to erythromycin, lincomycin, and tetracycline.

Pachymic acid promotes induction of autophagy related to IGF-1 signaling pathway in WI-38 cells.

Background: The insulin-like growth factor 1 (IGF-1) signaling pathway has spotlighted as a mechanism to elucidate aging associated with autophagy in recent years. Therefore, we have tried to screen an effective compound capable of inducing autophagy to delay aging process.

Purpose: The aim of this study is to investigate whether pachymic acid, a main compound in Poria cocos, induces autophagy in the aged cells.