Effects of Cystic Duct Margin Involvement on the Survival Rates of Patients With Gallbladder Cancer: A Propensity Score-Matched Case-Control Study.

Background In gallbladder cancer (GBC), extrahepatic bile duct (EHBD) resection is selectively performed if gross direct extension or microscopic involvement of the cystic duct margin (CDM) is detected. Although CDM is usually sent for frozen biopsy intraoperatively in most centers, there are no studies regarding the routine use of CDM frozen biopsy irrespective of the tumor location and paucity of literature regarding the impact of CDM status on recurrence-free and overall survival in GBC. The presence of obstructive jaundice in GBC usually indicates the involvement of EHBD or cystic duct-bile duct junction.

Surgery versus no surgery in stage IV gallbladder carcinoma: A propensity score-matched analysis.

Objectives: Patients with stage IV gallbladder cancer (GBC) have a dismal prognosis. Mostly, they are not amenable to surgical treatment. However, in some of them, a potentially curative surgical resection is possible.

A Pancreatic Hydatid Cysts Causing Recurrent Acute Pancreatitis Mimicking a Pancreatic Pseudocyst: A Case Report.

Hydatid disease is a zoonotic disease, mainly prevalent in endemic countries. The liver and lungs are the most commonly affected organs in hydatid disease. Primary hydatid cyst of the pancreas is rare, and pancreatitis due to hydatid cyst has rarely been listed in the literature.

De-novo transcriptome assembly and analysis of lettuce plants grown under red, blue or white light.

Lettuce (Lactuca sativa) is grown in various parts of the world for use as a leafy vegetable. Although the use of light-emitting diode (LED) in controlled plant production systems has been successfully used to enhance nutritional quality and plant growth efficiently, the molecular basis of lettuce's response to varying light spectra is not studied. Using next-generation sequencing, we have analyzed the transcriptomes of leaf lettuce (Lactuca sativa var.

Gallbladder Cancer With Jaundice: Surgery Versus No Surgery.

Background Patients with gallbladder carcinoma (GBC) and jaundice have a poor prognosis. The surgical management of these patients is controversial. There is a dearth of studies comparing curative surgical resection (CR) versus non-curative resection/palliation (NCR) in patients with GBC and jaundice.

A New Variant of Choledochal Cyst-Type 6B.

A choledochal cyst involving the cystic duct (type 6) is a rare disease. Dilatation of the common bile duct along with the involvement of cystic duct is extremely rare and only a few cases have been reported until now. A 38-year-old woman was evaluated for complaints of pain in the upper abdomen.

Osteoporosis in Parkinson's Disease: Relevance of Distal Radius Dual-Energy X-Ray Absorptiometry (DXA) and Sarcopenia.

Osteoporotic fractures are common in Parkinson's disease (PD). Standard dual-energy X-ray absorptiometry (DXA) measuring bone mineral density (BMD) at the femoral neck and lumbar spine (central sites) has suboptimal sensitivity in predicting fracture risk in the general population. An association between sarcopenia and osteoporosis in PD has not been studied.

Progressive and accelerated weight and body fat loss in Parkinson's disease: A three-year prospective longitudinal study.

Introduction: Although weight loss is common in Parkinson's disease (PD), longitudinal studies assessing weight and body composition changes are limited.

Methods: In this three-year longitudinal study, 125 subjects (77 PD patients and 48 spousal/sibling controls) underwent clinical, biochemical and body composition assessments using dual-energy X-ray absorptiometry.

Results: Patients were older than controls (65.

Statistical modeling of pullulan production and its application in pullulan acetate nanoparticles synthesis.

This work focused on the optimization of exo-polysaccharide, pullulan production by exploiting cassava bagasse, an agricultural solid waste residue by solid state fermentation and its application in the preparation of pullulan acetate nanoparticles. Statistical approach was investigated to maximize the pullulan production using C/N ratio, initial pH, NaCl and ZnSO4·5H2O. The optimum conditions for maximum yield of pullulan (39.

Needle safety awareness among dental nurses.

The objective of this study was to assess the prevalence of needlestick injury (NSI) and the awareness and attitudes of dental nurses in Cuddalore district, India, toward needle safety. Responses were gathered from 102 dental nurses via a questionnaire that included demographic data, the prevalence of NSIs in the past 6 months, their causes, responses of dental nurses to such injuries, and dental nurses' awareness of injection safety practices. Altogether, 33.

Statistical optimization of pullulan production from Asian palm kernel and evaluation of its properties.

Pullulan, a biodegradable exopolysaccharide, was produced from Asian Palmyra palm kernel by solid-state fermentation. Levels of medium variables, namely carbon to nitrogen ratio (C/N), pH, NaCl concentration and ZnSO4·5H2O concentration were optimized to maximize pullulan production using Box-Behnken design of experiments. Optimal values were predicted as: C/N ratio - 28.

Xylanase production from Bacillus aerophilus KGJ2 and its application in xylooligosaccharides preparation.

Xylanolytic enzyme was produced using a newly isolated Bacillus aerophilus KGJ2 and low cost lignocellulosic sources in solid state fermentation. Seven different agricultural residues (wheat bran, tea dust, saw dust, paper waste, cassava bagasse, rice straw and rice husk) and six nitrogen source namely yeast extract, beef extract, peptone, ammonium nitrate, ammonium sulphate, and ammonium chloride were examined for xylanase production. Upon initial screening, wheat bran and ammonium chloride were chosen as suitable carbon source and nitrogen source respectively.

Bioconversion of industrial solid waste--cassava bagasse for pullulan production in solid state fermentation.

The purpose of the work was to produce commercially important pullulan using industrial solid waste namely cassava bagasse in solid state fermentation and minimize the solid waste disposal problem. First, influence of initial pH on cell morphology and pullulan yield was studied. Effect of various factors like fermentation time, moisture ratio, nitrogen sources and particle size on pullulan yield was investigated.

Statistical studies on high molecular weight pullulan production in solid state fermentation using jack fruit seed.

The purpose of the work was to optimize the medium variables for maximizing pullulan production using jack fruit seed as a low cost substrate by Aureobasidium pullulans in solid state fermentation. Effects of K2HPO4, KH2PO4, ZnSO4·5H2O, MgSO4·7H2O, NaCl, (NH4)2SO4·5H2O, yeast extract, moisture content (%, w/w) in the production medium on pullulan production were studied using Plackett-Burman design. Production of pullulan was significantly affected by the medium variables namely KH2PO4, ZnSO4·5H2O, NaCl and moisture content (%, w/w).

Effect of cytokinins on in vitro multiplication of Sophora tonkinensis.

Objective: To determine the effects of different cytokinins at various concentrations on in vitro shoot multiplication of an important medicinal plant.

Methods: Nodal explants (1.5-2.

Production of pullulan by Aureobasidium pullulans from Asian palm kernel: a novel substrate.

Production of a commercially important biodegradable polymer, pullulan, by Aureobasidium pullulans from four agricultural wastes namely wheat bran, rice bran, coconut kernel and palm kernel was evaluated in solid state fermentation. Under the experimental conditions, palm kernel resulted in highest concentration of pullulan (16 g/L) among the four solid substrates. Optimum initial pH and moisture content for pullulan production were found out to be 6.

Gait impairments in persons with multiple sclerosis across preferred and fixed walking speeds.

Objectives: To investigate (1) whether previously observed changes in gait parameters in individuals with multiple sclerosis (MS) are the result of slower preferred walking speeds or reflect adaptations independent of gait speed; and (2) the changes in spatiotemporal features of the unstable swing phase of gait in people with MS.

Design: Cross-sectional study assessing changes in gait parameters during preferred, slow (0.6m/s), medium (1.