Work Environment-related Stress Factors are Correlated with Diabetes Development in Workers with Impaired Glucose Tolerance: A 5-year Follow-up Study Using the Brief Job Stress Questionnaire (BJSQ).

Several previous studies have investigated the effects of occupational stress on the onset of diabetes mellitus (DM), but there are few studies of occupational stress and DM using the Brief Job Stress Questionnaire (BJSQ), a standard stress check method in Japan. This study aimed to determine the relationship between occupational stress factors and the onset of DM using the BJSQ. We examined 6,620 male company workers aged 40 years and above in 2013, using the BJSQ.

Long-term outcomes after intersphincteric resection for low-lying rectal cancer.

Background: As an anus-preserving surgery for very low rectal cancer, intersphincteric resection (ISR), has advanced markedly over the last 20 years. We investigated long-term oncologic, functional, and quality of life (QOL) outcomes after ISR with or without partial external sphincter resection (PESR).

Methods: A series of 199 patients underwent curative ISR with or without PESR between 2000 and 2008, with 49 receiving preoperative chemoradiotherapy (CRT group) and 150 undergoing surgery first (surgery group).

Effectiveness of a transanal tube for the prevention of anastomotic leakage after rectal cancer surgery.

Aim: We evaluated the effectiveness and safety of a transanal tube placed for the prevention of anastomotic leakage after rectal surgery.

Methods: Between 2007 and 2011, a total of 243 patients underwent anterior resection using the double stapling technique for rectal cancer at our institution. We excluded 67 patients with diverting stoma and divided the remaining patients into two groups: patients who did not receive a transanal tube and diverting stoma (n = 140; control group) and those who received a transanal tube (n = 36).

Efficacy of the predicted operation time (POT) strategy for synchronous colorectal liver metastasis (SCLM): feasibility study for staged resection in patients with a long POT.

Background: The optimal surgical strategy for resectable synchronous colorectal liver metastases (SCLM), whether simultaneous or staged resections, still remains obscure. The aim of this study was to assess the efficacy of the predicted operation time (POT) strategy, which recommends staged resections in case of POT ≥6 h, otherwise selecting simultaneous resection.

Methods: This was a prospective, nonrandomized, single-institution study.

Predictors for early recurrence after hepatectomy for initially unresectable colorectal liver metastasis.

Background: Early recurrence correlates with poor survival following various cancer surgeries and puts considerable stress on patients both physically and mentally. This retrospective study investigated the predictive factors for early recurrence after surgical resection for initially unresectable colorectal liver metastasis to elucidate indications for conversion strategies.

Methods: We retrospectively studied 46 patients who underwent hepatectomy after chemotherapy for initially unresectable colorectal liver metastasis from 1997 to 2010.

Association between anal function and therapeutic effect after preoperative chemoradiotherapy followed by intersphincteric resection.

Background/aims: Preoperative chemoradiotherapy (CRT) for rectal cancer improves local control, but can also induce severe anal dysfunction after surgery. The goal of the study was to assess the relationship of the therapeutic effect of CRT with anal function and prognosis after intersphincteric resection (ISR).

Methods: The subjects were 37 patients with lower rectal cancer who underwent ISR with preoperative CRT.

Incidence and predictive factors for pulmonary metastases after curative resection of colon cancer.

Purpose: To assess the actuarial incidence of pulmonary metastases as the first site of metastasis after R0 resection of colon cancer and to clarify predictive factors for pulmonary metastases as the first site of metastasis.

Methods: Data for 746 patients who underwent R0 resection for colon cancer from 2000 to 2006 were reviewed. The mean duration of follow-up was 56.

Rectoseminal vesicle fistula as a rare complication after low anterior resection: a report of three cases.

A rectoseminal vesicle fistula is a rare complication after a low anterior resection for rectal cancer, usually developing in the outpatient postoperative period with pneumaturia, fever, scrotal swelling or testicular pain. A diagnostic water-soluble contrast enema, cystography and computed tomography reveal a tract from the rectum to the seminal vesicle. Anastomotic leakage is thought to be partially responsible for the formation of such tracts.

Laparoscopic surgery for palliative resection of the primary tumor in incurable stage IV colorectal cancer.

Background: The purpose of the study was to evaluate the feasibility and efficacy of laparoscopic palliative resection in patients with incurable stage IV colorectal cancer.

Methods: We reviewed 100 patients with incurable stage IV colorectal cancer who underwent palliative resection of the primary tumor between 2002 and 2009 at National Cancer Center Hospital East (NCCHE). Outcomes and postoperative course were compared between patients who underwent open and laparoscopic surgery.

Differences in tissue degeneration between preoperative chemotherapy and preoperative chemoradiotherapy for colorectal cancer.

Purpose: Preoperative chemoradiotherapy (CRT) for rectal cancer is administered to improve local control, but can also induce severe anal dysfunction after surgery, while preoperative chemotherapy that significantly reduces the primary lesion in rectal cancer has recently been developed. The aim of the study was to examine differences in the effects of preoperative CRT and chemotherapy on tissue degeneration of patients with colorectal cancer.

Methods: The subjects were 91 patients, including 68 with rectal cancer who underwent internal sphincteric resection with (n = 47, CRT group) or without (n = 21, control group) preoperative CRT, and 23 with colorectal cancer who received preoperative FOLFOX treatment.

Postoperative chylous ascites after colorectal cancer surgery.

Purpose: To evaluate the diagnosis, epidemiology, risk factors, and treatment of chylous ascites after colorectal cancer surgery.

Methods: Among 907 patients who underwent colorectal cancer resection at our institution between 2006 and 2009, chylous ascites developed in 9. We analyzed the clinical data for these 9 patients.

Surgical management of small bowel metastases from primary carcinoma of the lung.

Purpose: To investigate the treatment and outcomes in a series of seven cases of small bowel metastases from lung cancer.

Methods: A total of 4114 patients with lung cancer were referred to this institution from 1995 to 2005. Seven (0.

The association between anal function and neural degeneration after preoperative chemoradiotherapy followed by intersphincteric resection.

Background: Preoperative chemoradiotherapy for rectal cancer is administered to improve local control, but it can also induce severe anal dysfunction after surgery.

Objective: The goals of the study were to assess the influence of preoperative chemoradiotherapy on pathological findings and to examine the correlation of these findings with the cause of severe anal dysfunction after intersphincteric resection.

Design: Peripheral nerve degeneration was evaluated histopathologically with the use of hematoxylin and eosin-stained sections of surgical specimens after intersphincteric resection, based on karyopyknosis, vacuolar degeneration, acidophilic degeneration of cytoplasm, denucleation, and adventitial neuronal changes.

[Sphincter-saving resection for low rectal cancer].

R0 resection, preservation of the anal sphincter, and local control are considered to be the most important target criteria in rectal cancer surgery. Many efforts have been made in recent years to increase the rate of sphincter preservation by performing pull-through operations, ultra-low anterior resection (U-LAR), and intersphincteric resection (ISR). U-LAR is the standard surgery for patients with lower rectal cancer to preserve anal function.

Association between incisional surgical site infection and the type of skin closure after stoma closure.

Purpose: This study was performed to investigate the effect of subcuticular sutures on the incidence of incisional surgical site infection (SSI) after closure of a diverting stoma.

Methods: The study was carried out as a retrospective analysis of prospectively collected data from 51 patients who underwent closure of diverting stoma following resections of lower rectal cancer between January 2008 and December 2008. This study attempted to determine whether there was an association between the type of skin closure and the incidence of incisional SSI.

Predictive factors for pulmonary metastases after curative resection of rectal cancer without preoperative chemoradiotherapy.

Objective: The aim of this study was to clarify the actuarial incidence of pulmonary metastases and risk factors for pulmonary metastases after curative resection of rectal cancer without preoperative chemoradiotherapy.

Design: This study was a retrospective review.

Patients: Data for 314 patients who underwent R0 resection for rectal cancer without preoperative chemoradiotherapy from 2000 to 2006 were reviewed.

Male sexual dysfunction after rectal cancer surgery.

Purpose: The aims of the study were to determine the extent of male sexual dysfunction after surgical treatment of rectal cancer and to examine the outcome of postoperative treatment with sildenafil.

Methods: A prospective study was performed in patients who underwent attempted curative total mesorectal excision (TME) for low rectal cancers. Sexual function scores were determined by questionnaire preoperatively and at 3 and 12 months postoperatively.

Preliminary experience with bladder preservation for lower rectal cancers involving the lower urinary tract.

Background And Objectives: The aim of this study was to evaluate the feasibility of en bloc colorectal resection combined with radical prostatectomy as an alternative to total pelvic exenteration (TPE) for patients with locally advanced rectal cancer involving the lower urinary tract organs.

Methods: Twenty men with primary rectal cancer clinically involving the lower urinary tract organs underwent extended colorectal resection combined with radical prostatectomy. Data were entered prospectively into a database.

Factors influencing survival after complete resection of pulmonary metastases from colorectal cancer.

Background: The aim of this retrospective study was to determine the efficacy of complete (R0) resection for pulmonary metastases of colorectal carcinoma, and to clarify prognostic factors for survival that could be used to identify patients likely to benefit most from pulmonary resection.

Methods: Data on 113 patients who underwent R0 resection of pulmonary metastases from colorectal cancer were reviewed. Overall median follow-up was 49 (range 1-140) months.

Oncologic outcome of intersphincteric resection for very low rectal cancer.

Background: In 2000 we launched a prospective program of intersphincteric resection (ISR) for very low rectal cancer. In this study we compared the oncologic outcome of patients who underwent ISR with the outcome of patients who underwent abdominoperineal resection (APR).

Methods: The data of 202 patients with very low rectal cancer who underwent curative ISR (n = 132) or curative APR (n = 70) between 1995 and 2006 were analyzed.

Analysis of clinical factors associated with anal function after intersphincteric resection for very low rectal cancer.

Purpose: The purpose of this study was to identify factors that have a negative impact on anal function after intersphincteric resection.

Methods: We evaluated postoperative anal function in 96 patients with very lower rectal cancer who underwent intersphincteric resection by having patients fill out detailed questionnaires at 3, 6, 12, and 24 months after surgery. Univariate and multivariate analysis based on the Wexner incontinence score were used to identify factors associated with poor anal function after intersphincteric resection.

Positron emission tomography for preoperative staging in patients with locally advanced or metastatic colorectal adenocarcinoma in lymph node metastasis.

Background/aims: The impact of positron emission tomography was prospectively evaluated using 18 (F)-fluoro-deoxyglucose (FDG-PET) for the detection of lymph node (LN) metastasis in preoperative locally advanced colorectal adenocarcinoma, compared with computed tomography (CT) and pathologic findings.

Methodology: Fifty-three patients who were suspected of LN involvement by CT were staged preoperatively for LN metastasis using FDG-PET and CT. Regional LNs were classified into 3 groups, N1, N2-3, and N4, according to the Japanese General Rules for Clinical and Pathological Studies on Cancer of the Colon, Rectum and Anus (6th Edition).

Long-term survival in two cases of resected gastric metastasis of pulmonary pleomorphic carcinoma.

We report two pulmonary pleomorphic carcinoma patients both of which underwent surgical resection of solitary gastric metastases. A 69-year-old man developed anemia 5 months after right upper lobectomy for pulmonary pleomorphic carcinoma and gastric metastasis was detected endoscopically. He underwent distal gastrectomy and has survived for 5 years without any other recurrence or metastasis.

Influence of learning curve on short-term results after laparoscopic resection for rectal cancer.

Background: Technical difficulties have been encountered in laparoscopic surgery for the treatment of rectal cancer. There are fewer studies about the learning curve for laparoscopic rectal resection.

Methods: Between June 1995 and August 2007, 200 patients who were scheduled to undergo laparoscopic rectal resection for rectal cancer were enrolled in the study.