Congenital epithelial cysts of the iris stroma.

Although epithelial implantation cysts in the anterior chamber and iris have often been described, spontaneous congenital epithelial cysts of the iris stroma are not common. A cyst large enough to obstruct vision and cause amblyopia was removed surgically from a 6-month-old infant. The presence of goblet cells in th epithelium may be related to the embryologic source or the cells.

Glaucoma with trabecular melanocytosis.

A case of unilateral glaucoma with ocular melanocytosis was treated by repeated (two) trabeculectomies and iridocyclectomies at the same time to rule out malignant neoplasms. Histologic study indicated the presence of melanocytes typical of ocular melanocytosis. A review of the literature disclosed seven other cases of this kind.

HLA in pigment dispersion and glaucoma.

Histocompatibility antigen typing was performed on 12 Caucasian patients with the pigment dispersion syndrome. Increased prevalence of HLA-B13 and Bw17 that had been observed in a previous study (Becker et al. 1977) could not be confirmed in the present study.

The pseudoexfoliation syndrome.

A clinical and ultramicroscopic review, including discussion of both scanning and transmission microscopy of the lens in the exfoliation syndrome, suggests that the term pseudoexfoliation be retained. Involvement of the lens epithelium, and particularly, the pigment epithelium of the iris and the ciliary body epithelium are emphasized as being the likely sources of the exfoliative fibrils. A case of pseudoexfoliation syndrome in an eye with an eccentric pupil revealed that the granular material seen on the lens capsule occurs only where the iris is in contact with the lens surface and the process may even involve the central anterior capsule under proper conditions.

In appreciation of the contributions of Harry Searls Gradle.

The many contributions of Harry Searls Gradle (1883-1950) to ophthalmology are recalled by an author who was his protégé. A former student of Anton Elschnig's, Gradle taught unique surgical skills to those who worked directly with him. Furthermore, he lent his insights and brilliant organizational talents to the development of institutions and programs for the betterment of ophthalmic education and practice.

Results and complications of limbal trephination and subscleral trephination (trabeculectomy).

Limbal trephinations on 395 eyes were followed postoperatively for six months to 19 years. Excellent results were obtained in patients over the age of 35, particularly those in the 50 and older age group, with chronic open-angle and chronic angle-closure glaucoma. Results were poor in younger age groups and in those with secondary glaucoma, particularly where it was associated with inflammatory disease.

Limbal trephination: a twenty-year follow-up.

In this series the results of limbal trephination were excellent in patients over 35 years of age, particularly those in the 50 and older age group, with chronic open-angle and chronic angle-closure glaucoma. Results were poor in younger age groups and in those with secondary glaucoma, particularly when it was associated with inflammatory disease.

Onset of the exfoliation syndrome after intracapsular lens extraction.

Two patients who had previously been operated on for cataract and had been carefully observed for evidence of the exfoliation (or pseudoexfoliation) syndrome had continuing formation of exfoliative material on the anterior surface of the hyaloid and the pupil border several years later.

Management of eye movement restriction (particularly vertical) in dysthyroid myopathy.

Sixteen cases of vertical rectus muscle myopathy in dysthyroid patients are described. In mild cases without diplopia prisms may be adequate treatment. When uncomfortable diplopia is present surgery is indicated when the muscle dysfunction has become stable.

Anterior segment metastases from an ovarian choriocarcinoma.

A 28-year old woman with ovarian choriocarcinoma developed a uveitis in her left eye. Subsequently, a mass was observed in the anterior segment of that eye together with a subconjunctival mass that appeared to extend from it. Biopsy of the subconjunctival nodule showed two different cell types consistent with the cytotrophoblastic and syncytiotrophoblastic elements typical and choriocarcinoma.

Oculodentodigital dysplasia syndrome with angle-closure glaucoma.

A 14-year-old girl with typical oculodentodigital syndrome had been treated for chronic glaucoma for seven years. She had corneas measuring R.E.

Experiences with some modifications of cyclodialysis for aphakic glaucoma.

Continued attempts to improve the success rate with modifications of the cyclodialysis procedure have been made and described here. The results with a scleral pedicle insertion and with a long scleral incision parallel to the limbus were very poor. As a result of improvements in the technique of separating the ciliary body from the scleral spur by depressing the former mechanically and of using of meridional incision to avoid a scar barrier, I have returned to a modified Blaskovics procedure.

[Removal of intraocular tumors and cysts by deep lamellar resection (author's transl)].

A series of 28 cases is presented in which a relatively simple surgical procedure of deep lamellar resection of adjacent cornea and sclera is used to remove malignant or possibly malignant growths of the iris root, ciliary body and interior choroid and epithelial cysts and downgrowths. The technique was developed from the early trabeculectomy operation and has been used during the past 16 years. It was used to remove 16 epithelial implantation cysts, 2 benign tumors of the chamber angle, 7 malignant melanomas of the iris root, 1 malignant melanoma of the choroid and ciliary body and 2 epithelial downgrowths.

Geographic dark posterior fundus patches.

Nine cases of a newly recognized, probably not uncommon, anomaly of the retinal pigment epithelium have been observed over a four-year period. The lesions occur predominantly in black subjects. Some degree of hemoglobinopathy was present in all the black patients with geographic dark posterior fundus patches.

The exfoliation syndrome.

A clinical and ultramicroscopic review, including discussion of both scanning and transmission microscopy of the exfoliation syndrome, suggests that the term pseudoexfoliation be replaced by exfoliation syndrome. Involvement of the lens epithelium and, particularly, the pigment epithelium of the iris and the ciliary body epithelium are emphasized as being the likely sources of the exfoliative fibrils. A case of exfoliation syndrome in an eye with an eccentric pupil revealed that the granular material seen on the lens capsule occurs only where the iris is in contact with the lens surface and the process may even involve the central anterior capsule under proper conditions.