Knowledge distillation (KD) is a conventional method in the field of deep learning that enables the transfer of dark knowledge from a teacher model to a student model, consequently improving the performance of the student model. In randomized neural networks, due to the simple topology of network architecture and the insignificant relationship between model performance and model size, KD is not able to improve model performance. In this work, we propose a self-distillation pipeline for randomized neural networks: the predictions of the network itself are regarded as the additional target, which are mixed with the weighted original target as a distillation target containing dark knowledge to supervise the training of the model.
View Article and Find Full Text PDFThis paper proposes a three-stage online deep learning model for time series based on the ensemble deep random vector functional link (edRVFL). The edRVFL stacks multiple randomized layers to enhance the single-layer RVFL's representation ability. Each hidden layer's representation is utilized for training an output layer, and the ensemble of all output layers forms the edRVFL's output.
View Article and Find Full Text PDFIEEE J Biomed Health Inform
February 2023
Alzheimer's disease (AD) is one of the most known causes of dementia which can be characterized by continuous deterioration in the cognitive skills of elderly people. It is a non-reversible disorder that can only be cured if detected early, which is known as mild cognitive impairment (MCI). The most common biomarkers to diagnose AD are structural atrophy and accumulation of plaques and tangles, which can be detected using magnetic resonance imaging (MRI) and positron emission tomography (PET) scans.
View Article and Find Full Text PDFIEEE J Biomed Health Inform
October 2023
As per the latest statistics, Alzheimer's disease (AD) has become a global burden over the following decades. Identifying AD at the intermediate stage became challenging, with mild cognitive impairment (MCI) utilizing credible biomarkers and robust learning approaches. Neuroimaging techniques like magnetic resonance imaging (MRI) and positron emission tomography (PET) are practical research approaches that provide structural atrophies and metabolic variations.
View Article and Find Full Text PDFBackground: To evaluate the influence of Erbium, Chromium:Yttrium-Scandium-Gallium-Garnet (Er,Cr:YSGG) laser irradiation (2W 15Hz, 2W 25Hz) on Penetration Depth, Surface Roughness, Surface Morphology and Etching Pattern of enamel and to compare it with conventional acid etching.
Material And Methods: Sixty sound human premolars extracted for orthodontic reasons were used for this study. Penetration Depth and Surface Roughness between Acid Etched and Laser Etched Enamel were evaluated using Non-contact 3D- Profilometer .
Random Forest is an ensemble of decision trees based on the bagging and random subspace concepts. As suggested by Breiman, the strength of unstable learners and the diversity among them are the ensemble models' core strength. In this paper, we propose two approaches known as oblique and rotation double random forests.
View Article and Find Full Text PDFA man in his 70s presented to hospital with an acute kidney injury. He recently had started taking valacyclovir for treatment of shingles. The valacyclovir was stopped and his acute kidney injury improved.
View Article and Find Full Text PDFIEEE J Biomed Health Inform
October 2022
Deep learning for electroencephalogram-based classification is confronted with data scarcity, due to the time-consuming and expensive data collection procedure. Data augmentation has been shown as an effective way to improve data efficiency. In addition, contrastive learning has recently been shown to hold great promise in learning effective representations without human supervision, which has the potential to improve the electroencephalogram-based recognition performance with limited labeled data.
View Article and Find Full Text PDFIEEE J Biomed Health Inform
October 2022
Hospitals can predetermine the admission rate and facilitate resource allocation based on valid emergency requests and bed capacity estimation. The excess unoccupied beds can be determined with the help of forecasting the number of discharged patients. Extracting predictive features and mining the temporal patterns from historical observations are crucial for accurate and reliable forecasts.
View Article and Find Full Text PDFRescheduling is a necessary procedure for a flexible job shop when newly arrived priority jobs must be inserted into an existing schedule. Instability measures the amount of change made to the existing schedule and is an important metrics to evaluate the quality of rescheduling solutions. This paper focuses on a flexible job-shop rescheduling problem (FJRP) for new job insertion.
View Article and Find Full Text PDFDeveloping efficient evolutionary algorithms attracts many researchers due to the existence of optimization problems in numerous real-world applications. A new differential evolution algorithm, sTDE-dR, is proposed to improve the search quality, avoid premature convergence, and stagnation. The population is clustered in multiple tribes and utilizes an ensemble of different mutation and crossover strategies.
View Article and Find Full Text PDFIEEE Trans Cybern
October 2017
Deep neural network-based methods have recently achieved excellent performance in visual tracking task. As very few training samples are available in visual tracking task, those approaches rely heavily on extremely large auxiliary dataset such as ImageNet to pretrain the model. In order to address the discrepancy between the source domain (the auxiliary data) and the target domain (the object being tracked), they need to be finetuned during the tracking process.
View Article and Find Full Text PDFMultimodal optimization problems consists of multiple equal or comparable spatially distributed solutions. Niching and clustering differential evolution (DE) techniques have been demonstrated to be highly effective for solving such problems. The key challenge in the speciation niching technique is to balance between local solution exploitation and global exploration.
View Article and Find Full Text PDFIEEE Trans Cybern
October 2015
A new approach to generate oblique decision tree ensemble is proposed wherein each decision hyperplane in the internal node of tree classifier is not always orthogonal to a feature axis. All training samples in each internal node are grouped into two hyper-classes according to their geometric properties based on a randomly selected feature subset. Then multisurface proximal support vector machine is employed to obtain two clustering hyperplanes where each hyperplane is generated such that it is closest to one group of the data and as far as possible from the other group.
View Article and Find Full Text PDFIEEE Trans Neural Netw Learn Syst
August 2016
Wind energy is a clean and an abundant renewable energy source. Accurate wind speed forecasting is essential for power dispatch planning, unit commitment decision, maintenance scheduling, and regulation. However, wind is intermittent and wind speed is difficult to predict.
View Article and Find Full Text PDFDifferential evolution (DE) is one of the most powerful stochastic real parameter optimizers of current interest. In this paper, we propose a new mutation strategy, a fitness-induced parent selection scheme for the binomial crossover of DE, and a simple but effective scheme of adapting two of its most important control parameters with an objective of achieving improved performance. The new mutation operator, which we call DE/current-to-gr_best/1, is a variant of the classical DE/current-to-best/1 scheme.
View Article and Find Full Text PDFSome creatures living in extremely low temperatures can produce some special materials called "antifreeze proteins" (AFPs), which can prevent the cell and body fluids from freezing. AFPs are present in vertebrates, invertebrates, plants, bacteria, fungi, etc. Although AFPs have a common function, they show a high degree of diversity in sequences and structures.
View Article and Find Full Text PDFKnowledge of three dimensional structure is essential to understand the function of a protein. Although the overall fold is made from the whole details of its sequence, a small group of residues, often called as structural motifs, play a crucial role in determining the protein fold and its stability. Identification of such structural motifs requires sufficient number of sequence and structural homologs to define conservation and evolutionary information.
View Article and Find Full Text PDFApoptosis is an essential process for controlling tissue homeostasis by regulating a physiological balance between cell proliferation and cell death. The subcellular locations of proteins performing the cell death are determined by mostly independent cellular mechanisms. The regular bioinformatics tools to predict the subcellular locations of such apoptotic proteins do often fail.
View Article and Find Full Text PDF3-dimensional domain swapping is a mechanism where two or more protein molecules form higher order oligomers by exchanging identical or similar subunits. Recently, this phenomenon has received much attention in the context of prions and neurodegenerative diseases, due to its role in the functional regulation, formation of higher oligomers, protein misfolding, aggregation etc. While 3-dimensional domain swap mechanism can be detected from three-dimensional structures, it remains a formidable challenge to derive common sequence or structural patterns from proteins involved in swapping.
View Article and Find Full Text PDFReal-world datasets commonly have issues with data imbalance. There are several approaches such as weighting, sub-sampling, and data modeling for handling these data. Learning in the presence of data imbalances presents a great challenge to machine learning.
View Article and Find Full Text PDFLipocalins are functionally diverse proteins that are composed of 120-180 amino acid residues. Members of this family have several important biological functions including ligand transport, cryptic coloration, sensory transduction, endonuclease activity, stress response activity in plants, odorant binding, prostaglandin biosynthesis, cellular homeostasis regulation, immunity, immunotherapy and so on. Identification of lipocalins from protein sequence is more challenging due to the poor sequence identity which often falls below the twilight zone.
View Article and Find Full Text PDFX-ray crystallography is the most widely used method for protein 3-dimensional structure determination. Selection of target protein that can yield high quality crystal for X-ray crystallography is a challenging task. Prediction of protein crystallization propensity from sequence information is useful for the selection of target protein for crystallization.
View Article and Find Full Text PDFEukaryotic protein secretion generally occurs via the classical secretory pathway that traverses the ER and Golgi apparatus. Secreted proteins usually contain a signal sequence with all the essential information required to target them for secretion. However, some proteins like fibroblast growth factors (FGF-1, FGF-2), interleukins (IL-1 alpha, IL-1 beta), galectins and thioredoxin are exported by an alternative pathway.
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