Retromode Infrared Scanning Laser Ophthalmoscopy in Vogt-Koyanagi-Harada Disease.

Purpose: This study examined six patients with Vogt-Koyanagi-Harada (VKH) disease using retromode infrared scanning laser ophthalmoscopy (RMI-SLO).

Methods: We conducted a single-center retrospective review of the medical records of six patients diagnosed with VKH disease. The RMI-SLO images were compared to those obtained using color fundus photography, optical coherence tomography (OCT), and dye-based retinal angiography.

Enhanced Electrochemical Performances of Heterostructures Based on the Colloidal Association of Graphene Oxide and Titanium Disulfide Nanosheets.

Due to the large proliferation of electrical devices combined with the ecological transition for carbon neutrality in various modern countries, the demand for compact and efficient portable energy sources is continuously increasing. In this research work, we have developed electrochemical energy storage heterostructures based on graphene oxides (GOs) and titanium disulfide (TiS) nanosheets of different lateral sizes through a facile colloidal association thanks to the opposite electric charges of the two types of nanosheets. Large GO (LGO) served as a template system to organize TiS nanosheets at different loadings, of which incorporation prevented any restacking of the layered graphitic structure.

Graphene Oxide Sheets Decorated with Octahedral Molybdenum Cluster Complexes for Enhanced Photoinactivation of .

The emergence of multidrug-resistant microbial pathogens poses a significant threat, severely limiting the options for effective antibiotic therapy. This challenge can be overcome through the photoinactivation of pathogenic bacteria using materials generating reactive oxygen species upon exposure to visible light. These species target vital components of living cells, significantly reducing the likelihood of resistance development by the targeted pathogens.

Porous and Partially Dehydrogenated Fe -Containing Iron Oxyhydroxide Nanosheets for Efficient Electrochemical Nitrogen Reduction Reaction (ENRR).

The design and development of efficient catalysts for electrochemical nitrogen reduction reaction (ENRR) under ambient conditions are critical for the alternative ammonia (NH ) synthesis from N and H O, wherein iron-based electrocatalysts exhibit outstanding NH formation rate and Faradaic efficiency (FE). Here, the synthesis of porous and positively charged iron oxyhydroxide nanosheets by using layered ferrous hydroxide as a starting precursor, which undergoes topochemical oxidation, partial dehydrogenated reaction, and final delamination, is reported. As the electrocatalyst of ENRR, the obtained nanosheets with a monolayer thickness and 10-nm mesopores display exceptional NH yield rate (28.

Synthesis of a Hybrid Composed of Anisotropic Niobate Layers Modified with MoC Nanoparticles.

The hybrid composed of anisotropic niobate layers modified with MoC nanoparticles is synthesized by multistep reactions. The stepwise interlayer reactions for layered hexaniobate induce selective surface modification at the alternate interlayers, and the following ultrasonication leads to the formation of double-layered nanosheets. The further liquid phase MoC deposition with the double-layered nanosheets leads to the decoration of MoC nanoparticles on the surfaces of the double-layered nanosheets.

Role of HIKESHI on Hyperthermia for Castration-Resistant Prostate Cancer and Application of a Novel Magnetic Nanoparticle with Carbon Nanohorn for Magnetic Hyperthermia.

The prognosis of castration-resistant prostate cancer (CRPC) is technically scarce; therefore, a novel treatment for CRPC remains warranted. To this end, hyperthermia (HT) was investigated as an alternative therapy. In this study, the analysis focused on the association between CRPC and heat shock protein nuclear import factor "hikeshi (HIKESHI)", a factor of heat tolerance.

Au-Loaded Superparamagnetic Mesoporous Bimetallic CoFeB Nanovehicles for Sensitive Autoantibody Detection.

Construction of a well-defined mesoporous nanostructure is crucial for applying nonnoble metals in catalysis and biomedicine owing to their highly exposed active sites and accessible surfaces. However, it remains a great challenge to controllably synthesize superparamagnetic CoFe-based mesoporous nanospheres with tunable compositions and exposed large pores, which are sought for immobilization or adsorption of guest molecules for magnetic capture, isolation, preconcentration, and purification. Herein, a facile assembly strategy of a block copolymer was developed to fabricate a mesoporous CoFeB amorphous alloy with abundant metallic Co/Fe atoms, which served as an ideal scaffold for well-dispersed loading of Au nanoparticles (∼3.

Phase Transfer of Inorganic Nanosheets in a Water/2-Butanone Biphasic System and Lateral Size Fractionation via Stepwise Extractions.

Lateral size fractionation of niobate nanosheets derived from KNbO·3HO was achieved via phase transfer from the aqueous phase to the 2-butanone phase in a water/2-butanone biphasic system, in which tetra--dodecylammonium (TDDA) bromide was used as a phase transfer reagent. Phase transfer of the nanosheets was observed when the TDDA/[NbO] molar ratios were 0.6 and 1.

Confocal imaging of biomarkers at a single-cell resolution: quantifying 'living' in 3D-printable engineered living material based on Pluronic F-127 and yeast Saccharomyces cerevisiae.

Background: Engineered living materials (ELMs) combine living cells with non-living scaffolds to obtain life-like characteristics, such as biosensing, growth, and self-repair. Some ELMs can be 3D-printed and are called bioinks, and their scaffolds are mostly hydrogel-based. One such scaffold is polymer Pluronic F127, a liquid at 4 °C but a biocompatible hydrogel at room temperature.

Stress and motivation of cell processing operators: A pilot study of an online questionnaire survey.

Introduction: Cell processing operators (CPOs) are one of the most important human assets for the industrial development of regenerative therapy since cell processing is still carried out manually. However, investigating the psychological aspects of CPOs to take advantage of this important human asset has not been done. Thus, the objectives of the current study were, first, to investigate the attributes of CPOs, second, to identify the factors that give CPOs mental stress, and third, to identify the motivational factors of CPOs.

Constructing Fast Transmembrane Pathways in a Layered Double Hydroxide Nanosheets/Nanoparticles Composite Film for an Inorganic Anion-Exchange Membrane.

Anion-exchange membranes (AEMs) with high conductivity are crucial for realizing next-generation energy storage and conversion systems in an alkaline environment, promising a huge advantage in cost reduction without using precious platinum group metal catalysts. Layered double hydroxide (LDH) nanosheets, exhibiting a remarkably high hydroxide ion (OH) conductivity approaching 10 S cm along the in-plane direction, may be regarded as an ideal candidate material for the fabrication of inorganic solid AEMs. However, two-dimensional anisotropy results in a substantially low conductivity of 10 S cm along the cross-plane direction, which poses a hurdle to achieve fast ion conduction across the membrane comprising restacked nanosheets.

Two-Dimensional Metal-Organic Framework Superstructures from Ice-Templated Self-Assembly.

Here, we report the synthesis of two-dimensional (2D) layered metal-organic framework (MOF) nanoparticle (NP) superstructures via an ice-templating strategy. MOF NP monolayers and bilayers can be obtained by regulating the concentration of colloidal MOF NPs without any external fields during self-assembly. Adjacent polyhedral MOF NPs are packed and aligned through crystalline facets, resulting in the formation of a quasi-ordered array superstructure.

MOF-derived nanoporous carbons with diverse tunable nanoarchitectures.

Metal-organic frameworks (MOFs), or porous coordination polymers, are crystalline porous materials formed by coordination bonding between inorganic and organic species on the basis of the self-assembly of the reacting units. The typical characteristics of MOFs, including their large specific surface areas, ultrahigh porosities and excellent thermal and chemical stabilities, as well as their great potential for chemical and structural modifications, make them excellent candidates for versatile applications. Their poor electrical conductivity, however, has meant that they have not been useful for electrochemical applications.

Inorganic material-based Janus nanosheets: asymmetrically functionalized 2D-inorganic nanomaterials.

During the past decade, various inorganic material-based Janus nanosheets have been prepared and their applications have been proposed. Inorganic material-based Janus nanosheets have various advantages over polymer-based Janus nanosheets, including the maintenance of their characteristic two-dimensional shape, and are expected to be applied as unique functional materials. Methods for regioselective functionalization of the two sides of the individual nanosheets are extremely important for the development of inorganic material-based Janus nanosheets.

Soft Template-Based Synthesis of Mesoporous Phosphorus- and Boron-Codoped NiFe-Based Alloys for Efficient Oxygen Evolution Reaction.

Controlling the morphology, composition, and crystalline phase of mesoporous nonnoble metal catalysts is essential for improving their performance. Herein, well-defined P- and B-codoped NiFe alloy mesoporous nanospheres (NiFeB-P MNs) with an adjustable Ni/Fe ratio and large mesopores (11 nm) are synthesized via soft-template-based chemical reduction and a subsequent phosphine-vapor-based phosphidation process. Earth-abundant NiFe-based materials are considered promising electrocatalysts for the oxygen evolution reaction (OER) because of their low cost and high intrinsic catalytic activity.

Anti-skin-aging effects of human ceramides via collagen and fibrillin expression in dermal fibroblasts.

Intercellular lipids comprise mainly ceramides, known to enhance the barrier function of the stratum corneum. However, the activities of ceramides inside the skin have not yet been fully elucidated. Here we examined how the human ceramide mixture (HC123) functions in the dermis.

Direct production of polyhydroxybutyrate and alginate from crude glycerol by Azotobacter vinelandii using atmospheric nitrogen.

While biodiesel is drawing attention as an eco-friendly fuel, the use of crude glycerol, a byproduct of the fuel production process, has increasingly become a concern to be addressed. Here we show the development of a low-cost fermentation technology using an atmospheric nitrogen-fixing bacterium to recycle crude glycerol into functional biopolymers. Azotobacter vinelandii showed substantial growth on tap water-diluted crude glycerol without any pretreatment.

Preparation of biocompatible hydrogels reinforced by different nanosheets.

The impact of inorganic nanosheets with various chemical compositions and properties at different concentrations on the rheological properties and the gelation formation of a thermo-responsive hydrogel was investigated. F127 Pluronic triblock copolymers, with the structure (EO)(PO)(EO) (EO: ethylene oxide and PO propylene oxide respectively), functionalized by dimethacrylate (F127-DMA) at a concentration of 25% was used in this study. After careful characterization by complementary techniques: transmission electron microscopy (TEM), atomic force microscopy (AFM), and X-ray diffraction of nanosheets derived from the peeling of layered materials (montmorillonite, organoclays and hexaniobate), the nanosheets were seen to be suitably dispersed in the hydrogels.

Preparation of double-layered nanosheets containing pH-responsive polymer networks in the interlayers and their conversion into single-layered nanosheets through the cleavage of cross-linking points.

Double-layered nanosheets containing pH-cleavable polymer networks between two niobate layers were prepared by copolymerization of -isopropylacrylamide and an acid-degradable crosslinker surface-initiated atom transfer radical polymerization on the surface of hydrated interlayers (interlayer I) of KNbO·3HO and subsequent exfoliation by the introduction of tetra--butylammonium (TBA) ions into anhydrous interlayers (interlayer II). Moreover, the double-layered nanosheets were converted into single-layered nanosheets by the cleavage of cross-linking points in polymer networks by lowering pH. Fourier transform infrared spectroscopy (FTIR) and thermogravimetry (TG) results showed that polymer networks were present, and nanosheets with a thickness of 10.

Preparation of water-dispersible Janus nanosheets from KNbO·3HO and their behaviour as a two-dimensional surfactant on air-water and water-toluene interfaces.

KNbO·3HO-based Janus nanosheets with water dispersibility and surface activity were prepared sequential regioselective surface modification. To provide individual Janus nanosheets with these two properties, phenylphosphonic acid and phosphoric acid were utilized for surface modification at interlayers I and II of KNbO·3HO, respectively, and the resulting product was exfoliated into single-layered nanosheets by ultrasonication in water. The resulting aqueous dispersion of the Janus nanosheets showed lower surface tension than pure water, confirming that the Janus nanosheets had surface activity.

Crab-Eating Monkey Acidic Chitinase (CHIA) Efficiently Degrades Chitin and Chitosan under Acidic and High-Temperature Conditions.

Chitooligosaccharides, the degradation products of chitin and chitosan, possess anti-bacterial, anti-tumor, and anti-inflammatory activities. The enzymatic production of chitooligosaccharides may increase the interest in their potential biomedical or agricultural usability in terms of the safety and simplicity of the manufacturing process. Crab-eating monkey acidic chitinase (CHIA) is an enzyme with robust activity in various environments.

False recognition/misidentification of unfamiliar person after cerebral infarction: A case report.

An 84-year-old man manifested false recognition/misidentification of unfamiliar person after cardiogenic cerebral infarction. He had good visual and hearing acuity, no hemianopsia, unilateral spatial neglect and visual object agnosia. However, he was unable to remember faces of his rehabilitation therapists, and repeatedly misidentified other patients' visitors and therapists as his family members and friends, without recognizing his mistakes.

Efficient lithium-ion storage using a heterostructured porous carbon framework and its transmission electron microscopy study.

A heterostructured porous carbon framework (PCF) composed of reduced graphene oxide (rGO) nanosheets and metal organic framework (MOF)-derived microporous carbon is prepared to investigate its potential use in a lithium-ion battery. As an anode material, the PCF exhibits efficient lithium-ion storage performance with a high reversible specific capacity (771 mA h g at 50 mA g), an excellent rate capability (448 mA h g at 1000 mA g), and a long lifespan (75% retention after 400 cycles). The transmission electron microscopy (TEM) study demonstrates that its unique three-dimensional (3D) heterostructure can largely tolerate the volume expansion.

Heterostructuring Mesoporous 2D Iridium Nanosheets with Amorphous Nickel Boron Oxide Layers to Improve Electrolytic Water Splitting.

2D heterostructures exhibit a considerable potential in electrolytic water splitting due to their high specific surface areas, tunable electronic properties, and diverse hybrid compositions. However, the fabrication of well-defined 2D mesoporous amorphous-crystalline heterostructures with highly active heterointerfaces remains challenging. Herein, an efficient 2D heterostructure consisting of amorphous nickel boron oxide (Ni-B ) and crystalline mesoporous iridium (meso-Ir) is designed for water splitting, referred to as Ni-B /meso-Ir.