Birth order and childhood type 1 diabetes risk: a pooled analysis of 31 observational studies.

Background: The incidence rates of childhood onset type 1 diabetes are almost universally increasing across the globe but the aetiology of the disease remains largely unknown. We investigated whether birth order is associated with the risk of childhood diabetes by performing a pooled analysis of previous studies.

Methods: Relevant studies published before January 2010 were identified from MEDLINE, Web of Science and EMBASE.

Predictive factors of non-deterioration of glucose tolerance following a 2-year behavioral intervention.

Aim: To identify predictive factors associated with non-deterioration of glucose metabolism following a 2-year behavioral intervention in Japanese-Brazilians.

Methods: 295 adults (59.7% women) without diabetes completed 2-year intervention program.