Publications by authors named "Suelen Bianca Stopa Martins"
Article Synopsis
- The study aimed to assess the effectiveness of multiple-target therapy for treating posttransplant focal segmental glomerulosclerosis, as there is no agreed-upon treatment strategy.
- Thirteen patients underwent the therapy, with only 15.4% achieving complete or partial remission, while 38% faced graft loss within a year.
- High rates of treatment discontinuation (77%) were noted, primarily due to infections, with cytomegalovirus being the most common complication, indicating that the therapy's effectiveness was limited.
Efficacy and safety of single-dose anti-thymocyte globulin versus basiliximab induction therapy in pediatric kidney transplant recipients: A retrospective comparative cohort study.
Pediatr Transplant
May 2024
Background: This study aimed to compare the efficacy and safety of basiliximab (BAS) versus a single dose of anti-thymocyte globulin (r-ATG) induction therapy in pediatric kidney transplant recipients (KTRs).
Methods: This single-center retrospective comparative cohort study included all pediatric KTRs from May 2013 to April 2018 and followed up to 12 months. In the first period, all recipients received BAS, while from May 2016, a single 3 mg/kg dose of r-ATG was instituted.
Immunogenicity, Safety, and Clinical Effectiveness After 2 Doses of BNT162b2 Vaccine Among Pediatric Kidney Transplant Recipients Versus Healthy Volunteers: A Prospective Nonrandomized Study.
Transplantation
March 2023
The challenges of the pandemic and the vaccination against covid-19 in pediatric patients with kidney disease.
J Bras Nefrol
January 2023
The covid-19 vaccine confers direct protection and reduces transmission rates of the virus and new variants. Vaccines from Pfizer/BioNTech and CoronaVac have been cleared for children in Brazil. They are safe, effective, and immunogenic.
View Article and Find Full Text PDFTransplanting Kidneys From Donors With SARS-CoV-2 RNA Positivity in Brazil: Early Success Under a Detailed Surveillance Approach.
Transplantation
December 2022
Objective: This study aims to describe the result of the strategies adopted to maintain the transplant program amid the COVID-19 pandemic.
Methods: Since March 2020, several measures have been adopted sequentially, including the compulsory use of personal protective equipment and the real-time polymerase chain reaction testing of collaborators, symptomatic patients, potential deceased donors, candidates for recipients, and in-hospital readmissions, regardless of symptoms. The living-donor transplantation was restricted to exceptional cases.
The Brazilian collaborative registry for pediatric renal transplantation began in 2004 as a multicenter initiative aimed at analyzing, reporting, and disseminating the results of pediatric renal transplantation in Brazil. Data from all pediatric renal transplants performed from January 2004 to May 2018 at the 13 participating centers were analyzed. A total of 2744 pediatric renal transplants were performed in the thirteen participating centers.
View Article and Find Full Text PDFThe effect of anti-thymocyte globulin and everolimus on the kinetics of cytomegalovirus viral load in seropositive kidney transplant recipients without prophylaxis.
Transpl Infect Dis
August 2018
Background: The use of mTOR inhibitors is associated with lower incidence of CMV infections but its effect on viral load has not been investigated.
Aims, Materials And Methods: This post-hoc analysis included data from 273 CMV seropositive kidney transplant recipients randomized to receive anti-thymocyte globulin and everolimus (rAGT/TAC/EVR, n = 81), basiliximab and everolimus (BAS/TAC/EVR, n = 97) or basiliximab and mycophenolate (BAS/TAC/MPS, n = 95). All patients received tacrolimus (TAC) and corticosteroids.