An optimised method for the accurate determination of zeranol and diethylstilbestrol in animal tissues using isotope dilution-liquid chromatography/mass spectrometry.

Isotope dilution-liquid chromatography/mass spectrometry (ID-LC/MS) has been established as a candidate reference method for the accurate determination of growth promoters (zeranol, taleranol, and diethylstilbesterol) in raw meat samples. Sample preparation processes including an enzymatic hydrolysis, extraction, and SPE clean-up were optimised. The sensitivity difference of trans- and cis-diethylstilbestrol (isomerizing in sample preparation processes) by the LC/MS was measured by running a trans/cis mixture (ratio measured by a quantitative NMR) with and without sample matrices, and applied for the determination of total diethylstilbestrol.

Stereoselective synthesis of (+)-SCH 351448: a unique ligand system for sodium, calcium, and other cations.

(+)-SCH 351448 (Na+ salt A) was synthesized employing ring-closing olefin metathesis reaction of an open diene diester intermediate for construction of the 28-membered macrodiolide structure. The open diene diester was prepared from the monomeric hydroxy carboxylic acid and two different olefin fragments. The monomeric hydroxy acid was synthesized via Julia-Julia coupling reaction of intermediates derived from the same olefinic fragments.

Rhodium-catalyzed carbonylative [2+2+1] cycloaddition reactions: catalytic formation of bicyclic cyclohexenones [corrected].

The rhodium-catalyzed carbonylative [3+2+1] cycloaddition of trienes into bicyclohexenones has been developed. The carbonylated cycloaddition products have a high regioselectivity. This catalytic system tolerates functionalities including ether, sulfonamide, and ester.

A one-dimensional coordination polymer with metal-metal interactions: catena-poly[[triaquabarium(II)]-mu-aqua-kappa2O:O-di-mu-thiosalicylato-kappa4O:O].

In the title compound, [Ba(C(7)H(5)O(2)S)(2)(H(2)O)(4)](n), the Ba(II) atom lies on a mirror plane and is nine-coordinated by four bridging carboxylate O atoms of the thiosalicylate ligands, two bridging water molecules and three terminal water molecules. There is an intramolecular S-H.O hydrogen bond between the S and O atoms in the thiosalicylate ligand.

Catalytic one-pot synthesis of [5.5.5.6]fenestrane systems via a dicobalt octacarbonyl-catalyzed tandem cycloaddition of dienediynes.

Catalytic one-pot synthesis of fenestrane derivatives from dienediynes was developed: fenestranes were synthesized in high yields by a dicobalt octacarbonyl-catalyzed tandem cycloaddition of dienediynes.

Diaquabis(1,3-propanediamine-kappa(2)N,N')nickel(II) bis(sulfanilate).

The title compound, [Ni(C(3)H(10)N(2))(2)(H(2)O)(2)](C(6)H(6)NO(3)S)(2), contains alternating layers of sulfanilate anions and diaquabis(1,3-propanediamine)nickel(II) cations. The Ni atom lies on an inversion centre and is hexacoordinated by the 1,3-propanediamine ligands, which function as N,N'-bidentate ligands, and the water molecules, which are in a trans arrangement. The sulfanilate anions are arranged in layers, with the sulfonate and amine groups directed towards opposite sides of the layer.