A pilot study of predictive markers of chemotherapy-related amenorrhea among premenopausal women with early stage breast cancer.

Background: Premenopausal women treated for early stage breast cancer (ESBC) are at risk for chemotherapy-related amenorrhea (CRA). Prospectively-validated, predictive markers of CRA are needed.

Patients And Methods: Premenopausal women with ESBC and planned chemotherapy (>/= 25% risk of amenorrhea) were evaluated.