Accuracy of MRI R2* Mapping in Diagnosis of Liver Iron Concentration: A Meta-Analysis.

While current guidelines recommend R2* method as the first-line method for liver iron concentration (LIC) measurement, its diagnostic accuracy is debatable. A prior meta-analysis suggested limited accuracy of R2* method for identifying patients with iron overload. However, substantial advances in R2* method over the past decade may have improved its diagnostic performance.

Reproducibility of liver iron concentration measured by R2* method based on 1.5-T MRI: a meta-analysis.

Objectives: To explore the reproducibility of the 1.5-T MR imaging (MRI)-based R2* method in measuring the liver iron concentration (LIC) across different MRI scanners, scan parameters, and postprocessing techniques.

Materials And Methods: We performed a systematic search of the PubMed, Embase, Medline, Cochrane Library, and Web of Science databases and identified studies that used the 1.

18 F-FDG PET/CT of Intracholecystic Papillary Neoplasm in Cystic Neck and Duct.

We report 18 F-FDG PET/CT appearances of intracholecystic papillary neoplasm (ICPN) in the gallbladder neck and duct of a 74-year-old woman with a history of hepatitis B cirrhosis. The lesion presented with a large and sessile soft mass in the neck and duct of gallbladder with obvious glucose metabolism on PET/CT images, which was confirmed pathologically as ICPN (gastric foveolar type) with high-grade intraepithelial neoplasia. ICPN localized in the gallbladder neck and duct is extremely rare, and is easily misdiagnosed as gallbladder carcinoma.

The Clinical Significance of miR-135b-5p and Its Role in the Proliferation and Apoptosis of Hippocampus Neurons in Children with Temporal Lobe Epilepsy.

Temporal lobe epilepsy (TLE) is the most familiar localized epilepsy in children. MicroRNAs (miRNAs) are essential for the inhibition or promotion of numerous diseases. This study aimed to detect the expression of miR-135b-5p and primarily uncover its underlying function and mechanism in children with TLE.

Preoperative identification of microvascular invasion in hepatocellular carcinoma by XGBoost and deep learning.

Purpose: Microvascular invasion (MVI) is a valuable predictor of survival in hepatocellular carcinoma (HCC) patients. This study developed predictive models using eXtreme Gradient Boosting (XGBoost) and deep learning based on CT images to predict MVI preoperatively.

Methods: In total, 405 patients were included.

Multiphase convolutional dense network for the classification of focal liver lesions on dynamic contrast-enhanced computed tomography.

Background: The accurate classification of focal liver lesions (FLLs) is essential to properly guide treatment options and predict prognosis. Dynamic contrast-enhanced computed tomography (DCE-CT) is still the cornerstone in the exact classification of FLLs due to its noninvasive nature, high scanning speed, and high-density resolution. Since their recent development, convolutional neural network-based deep learning techniques has been recognized to have high potential for image recognition tasks.

Deep learning assisted differentiation of hepatocellular carcinoma from focal liver lesions: choice of four-phase and three-phase CT imaging protocol.

Purpose: To evaluate whether a three-phase dynamic contrast-enhanced CT protocol, when combined with a deep learning model, has similar accuracy in differentiating hepatocellular carcinoma (HCC) from other focal liver lesions (FLLs) compared with a four-phase protocol.

Methods: Three hundred and forty-two patients (mean age 49.1 ± 10.

Relationship between serotonin transporter gene polymorphism and constipation in cancer patients.

Introduction: To assess the potential association between serotonin transporter gene insertion/deletion polymorphism and the cancer-related constipation phenotype.

Material And Methods: A total of 120 patients diagnosed with malignant solid tumors were subjected to genotyping. For the two groups - patients with constipation and constipation-free patients with non-gastrointestinal cancer, 60 cases in each group - we collected the peripheral venous blood.