Background: Metabolic syndrome, a cluster of illnesses including insulin resistance, hyperlipidemia, hypertension, and central obesity, is affecting roughly a quarter of the world population. Dysregulation of iron homeostasis may be associated with insulin resistance, leading to metabolic syndrome. Uric acid is an antioxidant currently studied in relation to several metabolic disorders.
View Article and Find Full Text PDFThere is increasing interest in leveraging Earth Observation (EO) and geospatial data to predict and map aspects of socioeconomic conditions to support survey and census activities. This is particularly relevant for the frequent monitoring required to assess progress towards the UNs' Sustainable Development Goals (SDGs). The Sundarban Biosphere Reserve (SBR) is a region of international ecological importance, containing the Indian portion of the world's largest mangrove forest.
View Article and Find Full Text PDFSmall-molecule-based Cl ion carriers are gaining revived attention because of their recently discovered role toward anticancer activity. Herein, we showed that the anticancer agents, PITENINs, have an efficient transmembrane Cl ion transport activity. Theoretical calculations, H NMR titration, and spectrophotometric analysis suggest that the PITENINs strongly bind with a Cl ion.
View Article and Find Full Text PDFThe design of green synthetic reaction conditions is very challenging, especially for biomaterials, but worthwhile if the compounds can be easily synthesized in the aqueous medium. Herein, we report the development of sunlight-mediated thiol-ene/yne click reaction in the presence of a catalytic amount of -butyl hydroperoxide (TBHP) in an aqueous medium. The optimized reaction conditions were successfully applied to synthesize a series of small molecules and lipids in a single step in the aqueous medium.
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