Publications by authors named "Sudip Ray"

Retraction of 'Cytocompatible, soft and thick brush-modified scaffolds with prolonged antibacterial effect to mitigate wound infections' by Shaifali Dhingra , , 2022, , 3856-3877, https://doi.org/10.1039/D2BM00245K.

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Intermittent delivery of parathyroid hormone (PTH) could effectively promote bone regeneration, but the need for daily injection administration has limited its further clinical applications. Exposure to magnetic stimulation could regulate cell fate to promote osteogenesis. Herein, we developed a magnetized hydrogel with programmed PTH release and simultaneous magnetic actuation to promote osteogenic commitment.

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The benefits of honey have been recognized since ancient times for treating numerous diseases. However, in today's modern era, the use of traditional remedies has been rapidly diminishing due to the complexities of modern lifestyles. While antibiotics are commonly used and effective in treating pathogenic infections, their inappropriate use can lead to the development of resistance among microorganisms, resulting in their widespread prevalence.

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Correction for 'Cytocompatible, soft and thick brush-modified scaffolds with prolonged antibacterial effect to mitigate wound infections' by Shaifali Dhingra , , 2022, , 3856-3877, https://doi.org/10.1039/d2bm00245k.

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Biomedical device or implant-associated infections caused by pathogenic bacteria are a major clinical issue, and their prevention and/or treatment remains a challenging task. Infection-resistant antimicrobial coatings with impressive cytocompatibility offer a step towards addressing this problem. Herein, we report a new strategy for constructing highly antibacterial as well as cytocompatible mixed polymer brushes onto the surface of 3D printed scaffold made of biodegradable tartaric acid-based aliphatic polyester blends.

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Despite the extensive research, the moisture-based degradation of the 3D-printed polypropylene and polylactic acid blend is not yet reported. This research is a part of study reported on partial biodegradable blends proposed for large-scale additive manufacturing applications. However, the previous work does not provide information about the stability of the proposed blend system against moisture-based degradation.

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The materials for large scale fused filament fabrication (FFF) are not yet designed to resist thermal degradation. This research presents a novel polymer blend of polylactic acid with polypropylene for FFF, purposefully designed with minimum feasible chemical grafting and overwhelming physical interlocking to sustain thermal degradation. Multi-level general full factorial ANOVA is performed for the analysis of thermal effects.

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Additive manufacturing (AM) is a rapidly expanding material production technique that brings new opportunities in various fields as it enables fast and low-cost prototyping as well as easy customisation. However, it is still hindered by raw material selection, processing defects and final product assessment/adjustment in pre-, in- and post-processing stages. Spectroscopic techniques offer suitable inspection, diagnosis and product trouble-shooting at each stage of AM processing.

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Acrylonitrile butadiene styrene (ABS) is the oldest fused filament fabrication (FFF) material that shows low stability to thermal aging due to hydrogen abstraction of the butadiene monomer. A novel blend of ABS, polypropylene (PP), and polyethylene graft maleic anhydride (PE-g-MAH) is presented for FFF. ANOVA was used to analyze the effects of three variables (bed temperature, printing temperature, and aging interval) on tensile properties of the specimens made on a custom-built pellet printer.

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A chitosan-pectin (CS-PEC) biopolymeric hydrogel wound dressing was investigated for lidocaine delivery. Here we demonstrate for the first time the feasibility of three-dimensional (3D) printed CS-PEC hydrogel incorporating the local anaesthetic drug lidocaine hydrochloride (LDC) as a potential wound dressing candidate. The hydrogels were prepared by physical crosslinking of CS and PEC polysaccharides.

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This study reports on the fabrication of a controlled release system for the delivery of levonorgestrel (LNG) for long-term contraception. LNG was encapsulated in chemically cross-linked chitosan (CS) microspheres, and microspheres presented a spherical geometry with a good particle size distribution (polydispersity index (PDI) < 0.1).

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A potential nanograde antibiotic with hyperbranched architecture was synthesized from melt esterification of poly(ethylene glycol) or PEG and Citric acid or CA with 1:1 mol composition. PEG of different molecular weights, c.a.

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Customisation of sustained and controlled release of contraceptives plays a key role in veterinary applications. A biodegradable projectile containing different doses of contraceptive progesterone was prepared using fused deposition modelling 3D printing. Three concentrations of progesterone (2, 5 and 10% w/w) with polylactic acid was prepared as a 1.

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Background: A natural antioxidant derived from an agro-waste of the wine industry, grape tannin, was incorporated by melt blending into three different polyolefins (high-density polyethylene, linear low-density polyethylene and polypropylene) to introduce antioxidant functionality.

Results: Significant antioxidant activity was observed at 1% tannin inclusion in all polymer blends. The antioxidant activity was observed to increase steadily with a greater concentration of grape tannins, the highest increases being seen with polypropylene.

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Article Synopsis
  • * Heat curing at 150 °C for 24 hours altered the properties of the fiber mats based on the amount of gallic acid used, including a slower release rate of gallic acid.
  • * This research suggests that heat-cured zein-based fibers may be useful for food packaging applications due to their improved molecular structure and properties after treatment.
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The applicability of gallic acid loaded zein (Ze-GA) electrospun fibre mats towards potential active food packaging material was evaluated. The surface chemistry of the electrospun fibre mats was determined using X-ray photon spectroscopy (XPS). The electrospun fibre mats showed low water activity and whitish colour.

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Gallic acid was successfully incorporated into zein ultra-fine fibres at different loading amount (5%, 10% and 20%) in order to develop an encapsulating technology for functional ingredient delivery using electrospinning. The produced fibres exhibit diameters ranging from 327 to 387 nm. The physical and thermal properties of encapsulated gallic acid were determined by X-ray diffraction (XRD) and differential scanning calorimetry (DSC); and the interaction between gallic acid and zein was attested by attenuated total reflection-Fourier transform infrared (ATR-FTIR).

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Nanofibrous blends of HCl-doped poly(aniline-co-3-aminobenzoic acid) (3ABAPANI) copolymer and poly(lactic acid) (PLA) were fabricated by electrospinning solutions of the polymers, in varying relative proportions, in dimethyl sulfoxide/tetrahydrofuran mixture. The morphology, mechanical and electrical properties of the nanofibers were characterized and an assessment of their bioactivity performed. To assess cell morphology and biocompatibility, pure PLA and 3ABAPANI-PLA nanofibrous mats were deposited in the form of three-dimensional networks with a high degree of connectivity, on glass substrates, and their ability to promote proliferation of COS-1 fibroblast cells was determined.

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