New Calamitic Mesogens Exhibiting Aggregation-Induced Emission (AIE).

Aggregation-induced emitters or AIEgens are generally signified by their stronger photoluminescence in aggregation than in the solution state. Due to high emission efficiency in aggregate and solid states and good processability, organic AIEgens drew attention to the development of advanced luminescent materials. However, as mesogenic materials self-assemble to a different molecular arrangement in different phases, achieving liquid crystallinity and AIE properties in the same molecule would provide a valuable tool to develop solvent-independent AIEgenic materials.

2-Amino-4-(4-meth-oxy-phen-yl)-5-oxo-4,5-pyrano[3,2-]chromene-3-carbo-nitrile acetic acid monosolvate.

In the title co-crystal, CHNO·CHO, the expected proton transfer from acetic acid to amine has not occurred. In the crystal, the chromene mol-ecules are linked by N-H⋯O and N-H⋯N hydrogen bonds to generate [100] columns. The acetic acid mol-ecules form inversion dimers linked by pairwise O-H⋯O hydrogen bonds and occupy voids between the columns.

GC-MS profiling and bioactivity prediction of compounds from extract.

species are vegetable crops, belonging to the family of . For the present study plant samples of were collected from different parts of Barak Valley of Assam, India. Hyphenated technique Gas Chromatography-Mass Spectroscopy (GC-MS) of the chromatographically separated components of the plant extract was performed to identify some of the principles.

Conjugation of micro/nanocurcumin particles to ZnO nanoparticles changes the surface charge and hydrodynamic size thereby enhancing its antibacterial activity against Escherichia coli and Staphylococcus aureus.

Nanobiotechnology-mediated synthesis of ZnO nanoparticles, micro/nanocurcumin, and curcumin-ZnO nanocomposites and their characterization followed by comparative study of their antibacterial, antioxidant, and iron-chelating efficiency at various dosages are discussed. Micro/nanocurcumin and ZnO nanoparticles were synthesized using curcumin and zinc nitrate as precursor and then conjugated by sonication to synthesize curcumin-ZnO nanocomposites. The synthesized nanoparticles were then characterized by using ultraviolet-visible spectroscopy, X-ray diffraction, Scanning electron microscopy, Fourier-transform infrared spectroscopy, and dynamic light scattering analysis.

Self-assembly of silver nanoparticles through functionalization with coumarin-thiazole fused-ring thiol.

Self-assembly of nanoscale building blocks plays a critical role for the edifice of functional nanomaterials. In this work coumarin based fused-ring heterocyclic thiol functionalized silver nanoparticle exhibiting large self-assembly is reported. The particles spontaneously self-organise towards the formation of larger superstructures, yet still retaining their individual particle morphology (~10nm).

Molecular and in silico analysis of a new plasmid-mediated AmpC β-lactamase (CMH-2) in clinical isolates of Klebsiella pneumoniae.

Two Klebsiella strains isolated from urine samples were positive for bla by PCR and showed sequence similarity with CMH-1 (98.6%) after sequencing. It also shares 82% similarity with ACT-1, 85% with MIR-1 and 81% with the chromosomal AmpC gene of Enterobacter cloacae.

Computational analysis of the activity of pongachalcone I against highly resistant bacteria Pseudomonas putida.

TtgR is a multi-drug binding protein in the gram negative bacteria Pseudomonas putida (DOT-T1E strain) and regulates one of the key mechanisms of its antibiotic resistance by active extrusion of toxic compounds through the membrane-bound efflux pumps. The paper reports the molecular docking studies of Pongachalcone I, a natural pyranochalcone and reported potent inhibitor of the bacteria, on the transcriptional regulator (TtgR) enzyme (PDB Code: 2UXI) which is a key efflux pump TtgABC operon repressor. Although the bacterium is capable to expel antibiotics like Chloramphenicol, Tetracycline and Naringenin, yet Pongachalcone I has potent activity against it.