(L.) Delile, a member of the Zygophyllaceae family, is commonly known as the desert date. This tree is famous for yielding edible fruits and is esteemed for its nutritional richness and diverse health advantages.
View Article and Find Full Text PDFAntibiotic resistance is becoming more common, emphasising the demand for novel antibacterial treatments. The current investigation describes the green synthesis of graphene quantum dots (GQDs) using leaves and characterization via Fourier-transform infrared spectra (FTIR), X-ray diffraction (XRD), scanning electron microscope (SEM), transmission electron microscope (TEM), and ultraviolet-visible (UV-Vis) spectrophotometer. The results showed that GQDs are spherical in shape.
View Article and Find Full Text PDFUrease is an enzyme that plays a significant role in the hydrolysis of urea into carbonic acid and ammonia via the carbamic acid formation. The resultant increase in pH leads to the onset of various pathologies such as gastric cancer, urolithiasis, hepatic coma, hepatic encephalopathy, duodenal ulcers and peptic ulcers. Urease inhibitors can reduce the urea hydrolysis rate and development of various diseases.
View Article and Find Full Text PDFObesity is a serious health complication in almost every corner of the world. Excessive weight gain results in the onset of several other health issues such as type II diabetes, cancer, respiratory diseases, musculoskeletal disorders (especially osteoarthritis), and cardiovascular diseases. As allopathic medications and derived pharmaceuticals are partially successful in overcoming this health complication, there is an incessant need to develop new alternative anti-obesity strategies with long term efficacy and less side effects.
View Article and Find Full Text PDFDiabetes mellitus is a chronic metabolic disorder which results in increase of blood glucose level mainly due to insufficient insulin secretion or body fails to respond to secreted insulin from pancreatic cells. Diabetes is mainly the third cause of death worldwide after cardiovascular diseases and cancer. Nanotechnology is an emerging area in pharmaceutical sciences as nanoparticles are reported to increase the efficacy of drugs derived from plant resources by their target specific activity.
View Article and Find Full Text PDFLambda Cyhalothrin (LCT) is a type II synthetic pyrethroid widely used in agriculture, home pest control and protection of food stuff. Here, we evaluated its toxicity on biochemical parameters (Total protein, Acetyl cholinesterase, RNA and DNA) and liver histological alteration in mice after 24 h of oral administration @ 25, 50 and 75% of LD50 i.e.
View Article and Find Full Text PDFImidacloprid (IMD), 1(6-chloro-3-pyridinyl)methyl)-N-nitro-2-imidazolidinimine, was administered in female mice to study in vivo cytogenetic (chromosomal aberrations (CAs) and micronucleus assay) and hematological effects. The acute oral LD50 was determined to be 150 mg/kg bw in mice following OECD guidelines using AOT StatPgm425 software. The mice were administered orally with distilled water (negative control); mitomycin C (MMC), 1 mg/kg (positive control) and sub-lethal doses of 37.
View Article and Find Full Text PDFDrosophila ananassae has successfully invaded the cold and dry montane localities of the Western Himalayas in recent years. The ability of this desiccation- and cold-sensitive tropical species to evolve in response to seasonal changes in montane localities is largely unknown. Here, we investigated how this sensitive species adapt to seasonally varying environmental conditions that are lethal to its survival.
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