Publications by authors named "Sudheer Marrapu"
Chronic hepatitis B: Prevent, diagnose, and treat before the point of no return.
World J Hepatol
October 2024
Hepatitis B remains a significant global health challenge, contributing to substantial morbidity and mortality. Approximately 254 million people worldwide live with Chronic hepatitis B (CHB), with the majority of cases occurring in sub-Saharan Africa and the Western Pacific regions. Alarmingly, only about 13.
View Article and Find Full Text PDFBackground: Antituberculosis drug-induced liver injury (ATDILI) is a significant problem of tuberculosis treatment. This systematic review and meta‑analysis aimed at evaluating the incidence and risk factors of ATDILI in adult patients with tuberculosis in India.
Methods: Five electronic databases were searched comprehensively for studies on Indian adult patients with tuberculosis investigating the incidence and/or risk factors of ATDILI.
Article Synopsis
- Intestinal lymphangiectasia (IL) involves dilation of intestinal lymphatic vessels, leading to significant protein and nutrient loss, which can cause various deficiencies like hypoproteinemia and hypogammaglobulinemia.
- IL can be either primary (due to inherent lymphatic issues) or secondary (resulting from other medical conditions affecting lymphatic drainage), with secondary IL being more common than once thought.
- Diagnosis requires specific endoscopic and histological findings, and treatment is complex, often necessitating diet changes and medications such as sirolimus and octreotide to manage the condition effectively.
Patients with liver cirrhosis are advised to limit their sodium consumption to control excessive fluid accumulation. Salt is the most common form in which sodium is consumed daily. Consequently, various recommendations urge patients to limit salt intake.
View Article and Find Full Text PDFBackground: Although hydroxychloroquine (HCQ) lacks benefit in patients with moderate-to-severe COVID-19, its role in asymptomatic and mildly symptomatic disease needs better elucidation.
Methods: This multi-centre cohort study included asymptomatic and mildly symptomatic, RT-PCR confirmed COVID-19 cases between 30 March and 20 May, 2020. Patients were categorized into two groups (HCQ-treated and untreated) based on exposure to HCQ.