Publications by authors named "Sudhanshu Shekhar Mishra"
Background: It is well established that obesity is a major health risk in diabetes and associated diseases. Epigenetic changes, specially DNA methylation, play an important role in regulation of adipokines. The objective of the present study was to evaluate the DNA methylation status at the promoter region of the leptin gene in obese individuals and its association with metabolic risk factors.
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- Fibromyalgia patients experience significant sleep disturbances and poor sleep quality, which negatively affects their overall quality of life.
- The study included 30 fibromyalgia patients and 30 matched controls, using various assessments to evaluate sleep, quality of life, and autonomic function.
- Autonomic dysfunction was found in some patients but did not correlate with sleep issues or quality of life, indicating that sleep problems are a more pressing concern for those with fibromyalgia.