Publications by authors named "Sudhanshu P Singh"

The electrochemical determination of prednisolone has been investigated at fullerene-C(60)-modified gold (C(60)/Au) electrode and gold nanoparticles modified indium tin oxide (nano Au/ITO) electrode in phosphate buffer solution (PBS) of pH 7.2. During oxidation of prednisolone, an anodic peak with peak potential (E(p)) at 570 mV and 400 mV appeared at nano Au/ITO and C(60)/Au electrode, respectively.

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C(60)-modified glassy carbon electrode has been found to exhibit excellent electrocatalytic activity towards atenolol oxidation for its voltammetric determination at physiological pH. Lowering of overpotential associated with atenolol oxidation indicates electrocatalytic nature of electrode. Determination of atenolol was carried out at pH 7.

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Article Synopsis
  • A new method using a fullerene C60-modified glassy carbon electrode has been developed to accurately determine salbutamol levels, validated by GC-MS analysis.
  • The method shows a clear oxidation process of salbutamol that is pH-dependent, specifically optimized for physiological pH 7.4, with a linear detection range of 100-2000 ng/ml and a detection limit of 40 ng/ml.
  • This technique has been tested on human blood and urine samples and demonstrates high specificity and speed, effectively distinguishing salbutamol from common interferents, making it useful for doping detection in athletics.
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The electrochemical behavior of nandrolone decanoate (ND) at gold nanoparticles modified indium tin oxide (ITO) electrode was investigated. Oxidation of ND has been carried out in phosphate containing supporting electrolyte in the pH range 2.1-9.

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Voltammetric determination of adenine and guanine has been carried out at C60 modified glassy carbon electrode at physiological pH. Well-defined oxidation peaks were observed with Ep at approximately 990 mV and 692 mV for adenine and guanine respectively. Good colinearity was obtained in the concentration range 0.

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