Publications by authors named "Sudhair Abbas Bangash"
Article Synopsis
- The study investigates the antibiotic resistance profiles of oral bacteria in adults in Pakistan, noting the global health threat posed by such resistance, especially in developing countries.
- Conducted from January to December 2022, the research analyzed oral swabs from 240 adults who hadn't taken antibiotics recently, revealing significant resistance, particularly to penicillin, erythromycin, and tetracycline.
- Key findings indicate that older individuals and students displayed notably higher levels of antibiotic resistance, highlighting the need for better antibiotic management and awareness in these demographics.
Article Synopsis
- Cisplatin (CDDP) is a powerful anticancer drug but faces limitations due to resistance and serious side effects, leading to the development of a pH-sensitive calcium carbonate drug delivery system to enhance its efficacy while reducing toxicity.
- The new delivery system uses nanoparticles to co-deliver CDDP and oleanolic acid (OA), showing improved tumor effectiveness in laboratory tests on cells and in animal models compared to traditional free drug solutions.
- Studies indicate that this method not only protects against kidney damage often caused by CDDP but also allows for better targeting and prolonged presence of the drugs in tumor sites, making it a promising strategy for safer combination chemotherapy.
Cassia plants have a considerable position in conventional systems of medicine. The possible anti-nociceptive, anti-inflammatory, and anti-neuropathic properties of Cassia artemisiodes (CAD) extract were tested using the standard animal models. In this study, in vitro antioxidant, cyclooxygenase (COX-1 and 2), and 5-lipoxygenase (5-LOX) inhibitory assays were performed.
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