Aptamer-Based Diagnosis for Specific Malaria.

Malaria, caused by a protozoan parasite of the genus is a severe infectious disease with life-threatening consequences that has burdened mankind for centuries. Although () malaria is more prevalent globally than () malaria, India bears the largest burden of malaria, with over 3.6 million cases accounting for ∼48% of global malaria cases.

Task-sharing spinal anaesthesia care in three rural Indian hospitals: a non-inferiority randomised controlled clinical trial.

Background: Task-sharing of spinal anaesthesia care by non-specialist graduate physicians, termed medical officers (MOs), is commonly practised in rural Indian healthcare facilities to mitigate workforce constraints. We sought to assess whether spinal anaesthesia failure rates of MOs were non-inferior to those of consultant anaesthesiologists (CA) following a standardised educational curriculum.

Methods: We performed a randomised, non-inferiority trial in three rural hospitals in Tamil Nadu and Chhattisgarh, India.