Publications by authors named "Sudam S Mane"
Epimers can show different biological activities and different pharmacological behaviors; therefore, their separation and analysis are crucial in the drug development process. Due to their similar chemical and physical properties, separation of epimers is challenging. This study demonstrates the application of cyclic ion mobility-mass spectrometry to separate, identify, and quantify dexamethasone and betamethasone in a binary mixture.
View Article and Find Full Text PDFArticle Synopsis
- * Our study included tandem mass spectrometry to map out the relationships between precursor and fragment ions, allowing us to assign structures to major fragments resulting from the dissociation.
- * We proposed a benzyl migration mechanism based on computational analysis, offering insights into sparsentan's fragmentation pathways that could aid future research on similar molecules and their degradation products.