[Reflection of stable dominant states in the EEG of schizophrenic and alcoholic patients].

EEG was used to study stable dominant states in 12 patients with sluggish forms of schizophrenia and 11 alcoholics. The control group consisted of 15 normals. The patients demonstrated the following traits : deviations in the EEG readings, reflecting the interaction of different cortical zones; a complex of signs indicative of changes in the development of a generalized, nonspecific component of the activation reaction compared to data of the control group; a certain rigidity in the dominant-subdominant relationships.

[Effect of parenterally administered amino acids and protein hydrolysate on the electrical activity of brain structures].

Glycin, glutamic acid or casein hydrolysate induced high frequency and high voltage electrical waves in the brain-stem RF and often in the lateral hypothalamic nucleus and cortex. These changes were more obvious during feeding of the dogs. Sham feeding and parenteral administration of glucose or 0.

[Experimental reproduction of a secondary pacemaker center for alimentary motivation].

In chronic experiments on rabbits the possibility of artificial modeling of motivational feeding pacemaker's function by different limbic-reticular structures was investigated. It was shown that simultaneous stimulation of the lateral hypothalamic "feeding" centre with various structures of the limbic-reticular complex makes secondary pacemaker of feeding motivation in the midbrain reticular formation only.

[4-channel electroencephalographic amplifier with integrated microcircuits].

To conduct electroencephalographic investigations of stationary and moving objects a small-sized 4-channel amplifier built with integrated microcircuits has been developed. Each channel includes a pre-amplifier, main amplifier, calibrator, high and low frequency filters and a power pack. The adoption of integrated microcircuits enables it to locate the pre-amplifiers directly on the object of investigations.

[Role of motivational excitations in the integrative activity of individual cerebral neurons].

It has been shown that motivational excitation is a factor that changes the functional properties of brain single neurones. On the basis of ascending activating influences of the hypothalamic initiative centres, motivational excitation considerably changes convergent and discriminating properties of the cortical units. It is toward the cortical and subcortical neurones excitated by motivation that excitations evoked by reinforcing stimuli are directed.

[Modeling neuropathologic syndromes by creating generators of pathologically enhanced excitation in the hypothalamus of rabbits].

In the experiments on free behavior rabbits, tetanus toxin was injected into "pacemaker" motivational emotiogenic regions of the hypothalamus to form generators of pathologically enhanced excitation; this produced stable, long-term disorders in motivational-emotional behavior. The changes were manifested by intensification of the feeding behavior activity, including increase of the "secondary motivational reactions", intensification of the motor activity, excessive number of automatic masticatory movements, appearance of aggression, fear reaction and corresponding vegetative changes. The character of these reactions depended on the site of the toxin administration and on its dose.

Acute experimental emotional stress and natural history of arterial hypertension.

The role of experimental emotional stress in the genesis of arterial hypertension was studied. On immobilized rabbits during long-term electrical stimulation of the negative defence emotiogenic centers of the hypothalamus there was treaced development of the arterial hypertension from a transient phase of the struggle between pressor and depressor mechanisms to the phase of a stable dominance of pressor influences and effect on heart activity, including development of a sharp myocardial infarction. The role of different limbic and reticular structures, as well as of adrenal hormones and barocepor depressor mechanisms was revealed in dynamics of the arterial hypertension developmnet under hypothalamic stimulation.

[Hypnogenic action of a modulated electromagnetic field].

Behavioristic and electroencephalographic changes in rats under long-lasting modulated electromagnetic field (frequency of 40 MHz, modulation frequency 50 Hz, intensity 100--120 V/m) were studied. Some phasic disorders in the conditioned feeding and defense reactions were observed, including cataleptic state as a result of the action of modulated electromagnetic field. These behavioristic disorders are determined by the changes in the normal cortico-subcortical relationships.