In vitro and in silico cholinesterase inhibitory potential of metabolites from (Weber-van Bosse) M. Masuda.

Unlabelled: Alzheimer's disease (AD) is a neurodegenerative disease that causes deterioration in intelligence and psychological activities. Yet, till today, no cure is available for AD. The marine environment is an important sink of bioactive compounds with neuroprotective potential with reduced adverse effects.

The pro-inflammatory cytokine IL-Iβ alteration by deer () antler extract on osteoarthritis rat model.

Osteoarthritis is a disease associated with articular cartilage degradation, intra-articular area inflammation, and subchondral bone replacement. Cytokine IL-1β has a prominent function in the inflammations process that passes in the joints. The 70% ethanol extracts of deer antler (250 and 500 mg/kg BW) and glucosamine sulfate (250 kg/BW) were evaluated for four weeks in reducing cytokine IL-1β to rat model OA-induced Monosodium iodoacetate.

Nornidulin, A New Inhibitor of Malate: Quinone Oxidoreductase (MQO) from Indonesian sp. BioMCC f.T.8501.

This study aimed to obtain a microbial active compound as a novel antimalarial drug from Indonesian isolates. Target-based assays were used to screen for antimalarial activity against the parasite mitochondrial, malate:quinone oxidoreductase (MQO) enzyme. In total, 1600 crude extracts, composed from 800 fungi and 800 actinomycetes extracts, were screened against MQO, yielding six active extracts as primary hits.

The effect of deer antler from East Kalimantan to increase trabecular bone density and calcium levels in serum on osteoporotic mice.

Objectives: Glucocorticoid-induced osteoporosis (dexamethasone) is a primary cause of secondary osteoporosis by the decreasing formation and increasing resorption activities. Previously, the study showed that 70% ethanol and aqueous extract of deer antler have increased alkaline phosphatase in osteoblast cell that known as marker of bone formation. The mind of this study is to analyze the effect of deer antlers in increasing the bone trabecular density of osteoporosis-induced male mice.

Peel-off emulgel mask of L. Extract using gelling agent carbomer 940 as antiacne against ATCC 11827.

Linn., which contain lauric acid has been known had antibacterial activity against that usually improve severe of pimple. Current study investigated optimum formula of emulgel mask based on the L.

The Effect of Antler Deer Extracts from East Kalimantan in Bone Turnover Cell Models.

Objectives: Osteoporosis is a condition characterized by skeletal degradation of osseous tissue resulting in an escalated chance of broken bones. Traditionally, horn from East Kalimantan is used to treat many diseases, including conditions associated with bone turnover. The aim of the present research was to analyze the effects of 70% ethanol and aqueous extracts of antler's horn from East Kalimantan on nitric oxide inhibition, osteoblast differentiation, and mineralization related to bone turnover.