Publications by authors named "Subramaniam Poonguzhali"

Article Synopsis
  • * The research focused on comparing oven drying and freeze drying methods for creating orally disintegrating films (ODF) with memantine hydrochloride, assessing factors like the concentrations of Guar Gum, wheat starch, and PEG 400.
  • * The study found that the optimal ODF formulation—containing 1.50 g each of guar gum, starch, and PEG 400—was developed through freeze drying, resulting in a flexible, fast-disintegrating film that could effectively serve as an alternative medication delivery method for Alzheimer's treatment.
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The morbidity rate following a surgical procedure increasing rapidly in the cases associated with surgical site infections. Traditional sutures lack the ability to deliver drugs as the incorporation of the drug in their structure would hamper their mechanical properties. To prevent such infections, we developed an extracellular matrix mimicking electrospun nanofibrous yarns of poly-(D,L)-lactic acid and polyvinyl alcohol loaded with vancomycin and ferulic acid, prepared by uniaxial electrospinning technique.

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