Spotted fever group (SFG) Rickettsial infection has rarely been reported to develop severe central nervous system involvement. We report a case of meningoencephalitis presenting with fever, headache, drowsiness, seizures, and a skin rash, showing ELISA IgM positivity to SFG Rickettsia group. MRI brain showed multifocal bilateral asymmetric patchy areas of T2W/FLAIR hyperintensity with significant diffusion restriction.
View Article and Find Full Text PDFContext: Familial amyloidotic polyneuropathy (FAP) is often misdiagnosed as other neuropathic illnesses.
Aim: To highlight the diagnostic "odyssey" in three families of Indian origin with FAP.
Settings And Design: Cross-sectional, hospital-based study.
J Assoc Physicians India
June 2018
Introduction: The diagnosis of systemic sclerosis is mostly clinical and is identified by the various cutaneous changes. The cutaneous changes in systemic sclerosis are already well established and supported by a large number of studies and textbooks. Very few literatures describe foot findings in patients with systemic sclerosis.
View Article and Find Full Text PDFIntroduction: Among the modifiable risk factors for stroke, tobacco smoking is well recognized. In some studies the use of Smokeless Tobacco (ST) has also been contributed as a risk factor for ischemic stroke. Use of ST is very common in South-East Asia.
View Article and Find Full Text PDFContext: Multiple sclerosis (MS) has a spectrum of heterogeneity, as seen in western and eastern hemispheres, in the clinical features, topography of involvement and differences in natural history.
Aim: To study the clinical spectrum, imaging, and electrophysiological as well as cerebrospinal fluid (CSF) characteristics and correlate them with outcome.
Settings And Design: Retrospective analysis of MS patients during a period of 20 years.