Dosimetry of pulsed magnetic field towards attaining bacteriostatic effect on Enterococcus faecalis: Implications for endodontic therapy.

Aim: To examine in a laboratory setting the efficacy of moderate to high strength magnetic fields, as a potential bacteriostatic stimulus, against Enterococcus faecalis, one of the causative agents for infection during root canal treatments.

Methodology: Four different strengths (1, 2, 3 and 4 T) of the pulsed magnetic field (PMF) were applied in thirty repetitions to bacterial suspension. A pickup coil setup was used to measure the electromotive force induced inside the bacterial suspensions.

Effect of single and multilevel artificial inter-vertebral disc replacement in lumbar spine: A finite element study.

Degenerative disc disease (DDD) in lumbar spine is one of the major musculoskeletal disorders that cause low back pain (LBP). The intervertebral disc structure and dynamics of the lumbar spine are significantly affected by lumbar DDD, leading to a reduced range of motion (ROM), muscle weakness and gradual degradation. Spinal fusion and inter-vertebral disc replacement prostheses are two major surgical methods used for treating lumbar DDD.

Biomechanical Analysis to Probe Role of Bone Condition and Subject Weight in Stiffness Customization of Femoral Stem for Improved Periprosthetic Biomechanical Response.

Stress shielding due to difference in stiffness of bone and implant material is one among the foremost causes of loosening and failure of load-bearing implants. Thus far, femoral geometry has been given priority for the customization of total hip joint replacement (THR) implant design. This study, for the first time, demonstrates the key role of bone condition and subject-weight on the customization of stiffness and design of the femoral stem.

Periprosthetic biomechanical response towards dental implants, with functional gradation, for single/multiple dental loss.

The differences in shape and stiffness of the dental implants with respect to the natural teeth (especially, dental roots) cause a significant alteration of the periprosthetic biomechanical response, which typically leads to bone resorption and ultimately implant loosening. In order to avoid such clinical complications, the implant stiffness needs to be appropriately adapted. In this study, hollow channels were virtually introduced within the designed implant screws for reduction of the overall stiffness of the prototype.

Computational intelligence based design of implant for varying bone conditions.

The objective is to make the strain deviation before and after implantation adjacent to the femoral implant as close as possible to zero. Genetic algorithm is applied for this optimization of strain deviation, measured in eight separate positions. The concept of composite desirability is introduced in such a way that if the microstrain deviation values for all eight cases are 0, then the composite desirability is 1.

Finite Element Analysis to Probe the Influence of Acetabular Shell Design, Liner Material, and Subject Parameters on Biomechanical Response in Periprosthetic Bone.

The implant stability and biomechanical response of periprosthetic bone in acetabulum around total hip joint replacement (THR) devices depend on a host of parameters, including design of articulating materials, gait cycle and subject parameters. In this study, the impact of shell design (conventional, finned, spiked, and combined design) and liner material on the biomechanical response of periprosthetic bone has been analyzed using finite element (FE) method. Two different liner materials: high density polyethylene-20% hydroxyapatite-20% alumina (HDPE-20%HA-20%Al2O3) and highly cross-linked ultrahigh molecular weight polyethylene (HC-UHMWPE) were used.

Optimal selection of dental implant for different bone conditions based on the mechanical response.

Purpose: Bone quality varies from one patient to another extensively. Young's modulus may deviate up to 40% of normal bone quality, which results into alteration of bone stiffness immensely. The prime goal of this study is to design the optimum dental implant considering the mechanical response at bone implant interfaces for a patient with specific bone quality.

Microstructure and compression properties of 3D powder printed Ti-6Al-4V scaffolds with designed porosity: Experimental and computational analysis.

The osseointegration of metallic implants depends on an effective balance among designed porosity to facilitate angiogenesis, tissue in-growth and bone-mimicking elastic modulus with good strength properties. While addressing such twin requirements, the present study demonstrates a low temperature additive manufacturing based processing strategy to fabricate Ti-6Al-4V scaffolds with designed porosity using inkjet-based 3D powder printing (3DPP). A novel starch-based aqueous binder was prepared and the physico-chemical parameters such as pH, viscosity, and surface tension were optimized for drop-on-demand (DOD) based thermal inkjet printing.