Objective: The purpose of this study is to present a series of 46 cases of ameloblastoma-38 in mandible and 8 in maxilla treated in the Oral and Maxillofacial Surgery Department of Government Dental College and Hospital, Nagpur during 1997-2006 with emphasis on various treatment modalities used in treating different types of ameloblastoma and how to define the safe margin for different clinical and histopathological types of ameloblastoma with their follow-up.
Method: Confirmation of lesion done by incisional biopsy upon which treatment plan was decided and if resection is done then section was studied for amount of infiltration in adjoining bone histopathologically.
Result: In a follow-up period of 1-9 years recurrence was observed in six cases, two in patients treated with enucleation and curettage, three in patients treated with segmental resection and one in patient with peripheral ameloblastoma treated with soft tissue resection.