Publications by authors named "Subhashis Mondal"
Article Synopsis
- Altering the reactivity of molecules could resolve current limitations, especially for Donor-Acceptor Cyclopropanes (DACs) which have relied on Lewis acids for activation.
- Unpolarized alkenes present challenges due to a polarity mismatch with the Lewis acid-mediated zwitterionic intermediate, hindering their coupling.
- Using photoredox catalysis to leverage the distonic radical cation approach successfully navigates this mismatch, allowing for the formation of highly substituted cyclopentanes and facilitating new pathways to create bicyclo[3.1.1]heptanes through a unique [3σ+2σ] cycloaddition process.
1,n-dicarbonyls are one of the most fascinating chemical feedstocks finding abundant usage in the field of pharmaceuticals. Besides, they are utilized in a plethora of synthesis in general synthetic organic chemistry. A number of 'conventional' methods are available for their synthesis, such as the Stetter reaction, Baker-Venkatraman rearrangement, oxidation of vicinal diols, and oxidation of deoxybenzoins, synonymous with unfriendly reagents and conditions.
View Article and Find Full Text PDFOrganic photoredox-catalyzed alkylamination of olefins is performed with alkyl halides and nitrile solvent by blocking the traditional photoredox-ATRA process with Zn(OAc). A range of carbon-centered radicals (α-alkylcarbonyl, benzyl, cyanomethyl) are effectively participating in this strategy giving rise to versatile carboamination products with high synthetic value.
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